Agapejev Svetlana
Departamento de Neurologia e Psiquiatria, Faculdade de Medicina de Botucatu, Universidade Estadual de São Paulo, Botucatu, Brasil.
Arq Neuropsiquiatr. 2003 Sep;61(3B):822-8. doi: 10.1590/s0004-282x2003000500022. Epub 2003 Oct 28.
With the objective to show the characteristics of neurocysticercosis (NCC) in Brazil, was performed a critical analysis of national literature which showed a frequency of 1.5% in autopsies and 3.0% in clinical studies, corresponding to 0.3% of all admissions in general hospitals. In seroepidemiological studies the positivity of specific reactions was 2.3%. Brazilian patient with NCC presents a general clinical-epidemilogical profile (31-50 years old man, rural origin, complex partial epileptic crisis, increased protein levels or normal CSF, CT showing calcifications, constituting the inactive form of NCC), and a profile of severity (21-40 years old woman, urban origin, vascular headache and intracranial hypertension, typical CSF syndrome of NCC or alteration of two or more CSF parameters, CT showing vesicles and/or calcifications, constituting the active form of NCC). Although two localities from the state of S o Paulo have 72:100000 and 96:100000/habitants as prevalence coefficients, regional and national prevalences are very underestimated. Some aspects related to underestimation of NCC prevalence in Brazil are discussed.
为了展现巴西神经囊尾蚴病（NCC）的特征，对国内文献进行了批判性分析，结果显示尸检中该病的发生率为1.5%，临床研究中为3.0%，相当于综合医院所有入院病例的0.3%。在血清流行病学研究中，特异性反应的阳性率为2.3%。巴西NCC患者呈现出一般临床流行病学特征（31至50岁男性，来自农村，复杂部分性癫痫发作，脑脊液蛋白水平升高或正常，CT显示钙化，构成NCC的非活动形式）以及严重程度特征（21至40岁女性，来自城市，血管性头痛和颅内高压，典型的NCC脑脊液综合征或两个或更多脑脊液参数改变，CT显示囊泡和/或钙化，构成NCC的活动形式）。尽管圣保罗州的两个地区患病率系数分别为72/100000和96/100000，但区域和全国患病率被严重低估。文中讨论了巴西NCC患病率被低估的一些相关因素。
