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腐蚀埃肯菌引起的肺脓肿:一例报告

Lung abscess caused by Eikenella corrodens: report of a case.

作者信息

Hsu C Y, Liu L L, Luh K T

出版信息

Taiwan Yi Xue Hui Za Zhi. 1989 Aug;88(8):828-31.

PMID:2687435
Abstract

Eikenella corrodens is a slow-growing, facultatively anaerobic, gram-negative bacillus. It is part of the normal flora of the human upper respiratory tract. We report a 68-year-old man who developed lung abscesses caused by E. corrodens while on long-term corticosteroid therapy for polymyositis. It was isolated by percutaneous transthoracic aspiration of an abscess under real-time sonographic guidance. The organism has a very unusual antimicrobial susceptibility: sensitive to penicillin, ampicillin, cephapirin, chloramphenicol, minocycline and erythromycin but resistant to clindamycin, oxacillin and gentamicin. The patient was treated empirically with penicillin G and gentamicin. The latter was discontinued after the results of the bacterial culture and sensitivity test were available. He was discharged one month later with marked improvement. Our report clearly demonstrates that E. corrodens can be the sole pathogen of a respiratory tract infection.

摘要

啮蚀艾肯菌是一种生长缓慢、兼性厌氧的革兰氏阴性杆菌。它是人类上呼吸道正常菌群的一部分。我们报告一名68岁男性,他在接受治疗多发性肌炎的长期皮质类固醇治疗期间发生了由啮蚀艾肯菌引起的肺脓肿。通过在实时超声引导下经皮经胸穿刺抽吸脓肿分离出该菌。该菌具有非常不寻常的抗菌敏感性:对青霉素、氨苄西林、头孢匹林、氯霉素、米诺环素和红霉素敏感,但对克林霉素、苯唑西林和庆大霉素耐药。患者经验性使用青霉素G和庆大霉素治疗。在获得细菌培养和药敏试验结果后停用了后者。他一个月后出院,病情明显改善。我们的报告清楚地表明,啮蚀艾肯菌可以是呼吸道感染的唯一病原体。

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