Parekh Priti I, Blumenthal James A, Babyak Michael A, Merrill Kari, Carney Robert M, Davis R Duane, Palmer Scott M
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.
Chest. 2003 Nov;124(5):1682-8. doi: 10.1378/chest.124.5.1682.
To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation.
Duke University Medical Center/Lung Transplantation Program.
One hundred patients with end-stage pulmonary disease listed for lung transplantation.
Twenty-five percent (n = 25) of the sample met diagnostic criteria for at least one current mood or anxiety disorder. Controlling for age, gender, ethnicity, percentage of predicted FEV, and lung disease diagnosis, patients with a current psychiatric diagnosis reported poorer general quality of life (p < 0.0001), poorer disease-specific quality of life (p < 0.0001), greater shortness of breath (p = 0.01), more symptoms of psychological distress (p < 0.0001), lower levels of social support (p < 0.0001), and fewer positive health habits (p < 0.04) than their counterparts without a psychiatric diagnosis.
Psychiatric comorbidity affects a significant portion of patients awaiting lung transplantation and is associated with decreased health-related quality of life.
探讨等待肺移植患者的精神共病与生活质量之间的关系。
杜克大学医学中心/肺移植项目。
100例登记等待肺移植的终末期肺病患者。
25%（n = 25）的样本符合至少一种当前心境或焦虑障碍的诊断标准。在控制年龄、性别、种族、预计第一秒用力呼气容积百分比和肺病诊断后，当前有精神疾病诊断的患者报告的总体生活质量较差（p < 0.0001），疾病特异性生活质量较差（p < 0.0001），呼吸急促更严重（p = 0.01），心理困扰症状更多（p < 0.0001），社会支持水平更低（p < 0.0001），积极健康习惯更少（p < 0.04），与无精神疾病诊断的患者相比。
精神共病影响了相当一部分等待肺移植的患者，并与健康相关生活质量下降有关。
