Mustafa Amun, Karamat Asifa, Toor Wajeeha Mustansar, Mustafa Tehmina
Department of Medicine, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore 54000, Pakistan.
Department of Pulmonology, Gulab Devi Teaching Hospital, Lahore 54000, Pakistan.
Adv Respir Med. 2025 Jun 2;93(3):12. doi: 10.3390/arm93030012.
Depression and anxiety are common in patients with chronic respiratory diseases (CRDs), but their prevalence in intensive care settings, particularly in low-resource regions, remains underexplored.
To assess the prevalence and severity of depression and anxiety in patients with CRDs admitted to an intensive care unit (ICU) and identify associated factors.
A cross-sectional study was conducted at Gulab Devi Teaching Hospital, Lahore, Pakistan. Adult patients with CRDs admitted to the ICU were assessed using the Hamilton Depression Rating Scale. Statistical analyses included Fisher's exact test, Mann-Whitney/Kruskal-Wallis tests, and logistic regression.
Depression was highly prevalent across all CRD categories: 83%, 89%, 84%, and 93% in obstructive, restrictive, infectious, and other respiratory disease categories, and severe depression in 16%, 18%, 14%, and 37%, respectively. Anxiety symptoms were also widespread (77-100%), with no significant differences across disease groups. Depression was significantly associated with older age ( < 0.001, OR 1.08) and anxiety symptoms ( < 0.001, OR 47.07). Female gender was linked to anxiety ( = 0.034, OR 4.17).
The high burden of depression and anxiety in ICU patients with CRDs underscores the need for routine psychiatric screening and integrated mental health care in critical-care settings.
抑郁症和焦虑症在慢性呼吸系统疾病（CRD）患者中很常见，但在重症监护环境中，尤其是在资源匮乏地区，它们的患病率仍未得到充分研究。
评估入住重症监护病房（ICU）的CRD患者中抑郁症和焦虑症的患病率及严重程度，并确定相关因素。
在巴基斯坦拉合尔的古拉布·德维教学医院进行了一项横断面研究。使用汉密尔顿抑郁量表对入住ICU的成年CRD患者进行评估。统计分析包括费舍尔精确检验、曼-惠特尼/克鲁斯卡尔-沃利斯检验和逻辑回归。
抑郁症在所有CRD类别中都非常普遍：阻塞性、限制性、感染性和其他呼吸系统疾病类别中的患病率分别为83%、89%、84%和93%，严重抑郁症的患病率分别为16%、18%、14%和37%。焦虑症状也很普遍（77%-100%），各疾病组之间无显著差异。抑郁症与年龄较大显著相关（<0.001，OR 1.08）和焦虑症状（<0.001，OR 47.07）。女性与焦虑症有关（=0.034，OR 4.17）。
CRD的ICU患者中抑郁症和焦虑症的高负担凸显了在重症监护环境中进行常规精神科筛查和综合精神卫生保健的必要性。
