Lawrence S J
Union Memorial Hospital, Baltimore, Md.
Orthopedics. 1992 Nov;15(11):1331-5. doi: 10.3928/0147-7447-19921101-12.
The incidence of Lyme disease is increasing. This spirochetal infection may frequently manifest itself with joint involvement without characteristic dermatologic signs or history of tick bite. Serologic testing remains unreliable. Oral or parenteral antibiotics remain the mainstay of treatment. Chronic arthritis develops in approximately 10% of patients with Stage III disease. Lyme arthritis must be considered in the differential diagnosis of patients with mono- or oligoarticular joint involvement, especially in children and young adults with possible tick exposure. Further advances in antimicrobial therapy and serologic testing are anticipated.
莱姆病的发病率正在上升。这种螺旋体感染常常表现为关节受累，而无特征性皮肤体征或蜱叮咬史。血清学检测仍然不可靠。口服或胃肠外抗生素仍然是主要的治疗方法。约10%的III期疾病患者会发展为慢性关节炎。在诊断单关节或寡关节受累的患者时，尤其是在可能接触蜱的儿童和年轻人中，必须考虑莱姆关节炎。预计抗菌治疗和血清学检测会有进一步进展。
