Diederich S, Roos N, Holst D, Schopp K, Zander J, Peters P E
Institut für Klinische Radiologie, Westfälische Wilhelms-Universität, Münster.
Radiologe. 1992 Nov;32(11):530-5.
We reviewed the chest radiographs and clinical data of 30 patients in an intensive care unit with legionellosis diagnosed by significant serological findings (n = 18), microscopic demonstration of the organism in the transtracheal aspirate (n = 5) or both (n = 7) and investigated the correlation between the identification of Legionella and signs of pulmonary infection. In 13 patients legionnaires' disease was diagnosed with a high degree of confidence. Typical radiographic findings included distal air space disease, which initially appeared to be unilateral, progressing towards bilateral infiltrates. Patchy infiltration at the onset of disease was followed by consolidation. Small pleural effusions were common, while no abscess formation was observed. Characteristically, infiltration persisted for weeks even with clinical convalescence. These radiological findings correspond well with observations in otherwise healthy patients with legionnaire's disease. In 10 patients the etiology of pulmonary infiltrates could not be identified. Seven patients did not develop radiological or clinical signs of pneumonia; therefore, the serological/microscopic detection of Legionella was not interpreted as legionnaires' disease. According to the results of our investigation the diagnosis of legionnaires' disease requires radiological findings in addition to laboratory data.
我们回顾了重症监护病房中30例军团病患者的胸部X光片和临床资料,这些患者通过显著的血清学检查结果确诊(n = 18),通过经气管抽吸物中微生物的显微镜检查确诊(n = 5),或两者兼具(n = 7),并研究了军团菌鉴定与肺部感染体征之间的相关性。13例患者被高度确信诊断为军团病。典型的影像学表现包括远端气腔疾病,最初似乎是单侧的,随后发展为双侧浸润。疾病初期的斑片状浸润随后出现实变。少量胸腔积液很常见,未观察到脓肿形成。其特征是,即使临床症状已恢复,浸润仍持续数周。这些影像学表现与其他健康军团病患者的观察结果非常吻合。10例患者肺部浸润的病因无法确定。7例患者未出现肺炎的影像学或临床体征;因此,军团菌的血清学/显微镜检测未被解释为军团病。根据我们的调查结果,军团病的诊断除实验室数据外还需要影像学表现。