Handzel Thomas, Karanja Diana M S, Addiss David G, Hightower Allen W, Rosen Daniel H, Colley Daniel G, Andove Julius, Slutsker Laurence, Secor W Evan
Epidemic Intelligence Service, Division of Applied Public Health Training, Epidemiology Program Office, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Am J Trop Med Hyg. 2003 Sep;69(3):318-23.
A survey of 1,246 children 10-12 years old in 32 primary schools in Kenya near Lake Victoria was conducted to determine prevalence and distribution of schistosome and geohelminth infections. Stool and urine samples were collected and examined for eggs of Schistosoma mansoni, S. haematobium, and intestinal helminths. A questionnaire was used to obtain demographic information and to quantify exposure to surface waters. Houses, schools, and water sources were mapped using a geographic information system. The mean school prevalence of S. mansoni infection was 16.3% (range = 0-80%). Proximity to the lake (r = 0.89, P < 0.001) and contact with lake water were associated with infection, as were specific water-related activities including swimming, fishing, and collecting water. Sixty-three percent of students were infected with one or more other geohelminths and these infections were more homogenously distributed. The separate distributions of schistosome and geohelminth infections have important implications for combined mass-treatment programs.
在肯尼亚维多利亚湖附近的32所小学，对1246名10至12岁的儿童进行了一项调查，以确定血吸虫和土源性蠕虫感染的患病率及分布情况。采集了粪便和尿液样本，检测其中曼氏血吸虫、埃及血吸虫和肠道蠕虫的虫卵。使用问卷获取人口统计学信息，并量化地表水接触情况。利用地理信息系统绘制房屋、学校和水源的地图。曼氏血吸虫感染的学校平均患病率为16.3%（范围=0-80%）。靠近湖泊（r=0.89，P<0.001）以及接触湖水与感染相关，包括游泳、钓鱼和取水等特定与水相关的活动也与感染有关。63%的学生感染了一种或多种其他土源性蠕虫，这些感染分布更为均匀。血吸虫和土源性蠕虫感染的不同分布情况对联合群体治疗方案具有重要意义。
