Calero L, Brusis T
Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie der Kliniken der Stadt Köln, Krankenhaus Köln-Holweide.
Laryngorhinootologie. 2003 Nov;82(11):790-3. doi: 10.1055/s-2003-44546.
The CO (2)-Laser is an established and well-proven tool in the excision and vaporisation of laryngeal papillomatosis. Actually there exists only one report of an iatrogenous infection with the Human Papillomavirs (HPV) in a gynecological laser surgeon.
A 28-year-old gynecological operating room nurse, who assisted repeatedly in electrosurgical and lasersurgical excisions of anogenital condylomas, developed a recurrent and histologically proven laryngeal papillomatosis. The expert opinion of a virological institute confirmed a high probability of correlation between the occupational exposition and the laryngeal papillomatosis so that it was accepted as occupational disease. INFECTIVITY OF LASER PLUME: HPV-DNA has been repeatedly detected in laser-plume after excision of papillomas and condylomas. As of the present an exact proof that these particles are infectious has not been brought forward.
When following the recommended protective measures the potential risk of infection is estimated as very low for surgeons and nurses. The risk of exposition seems to be higher in gynecological interventions than in ENT because of the much larger tissue masses and because laser plume escapes easier into the room air when applying an open approach.
二氧化碳激光是用于喉乳头状瘤切除和汽化的一种成熟且经充分验证的工具。实际上，仅有一篇关于妇科激光外科医生发生人乳头瘤病毒（HPV）医源性感染的报告。
一名28岁的妇科手术室护士，多次协助进行肛门生殖器尖锐湿疣的电外科和激光外科切除手术，之后患上了复发性且经组织学证实的喉乳头状瘤。一家病毒学研究所的专家意见证实职业暴露与喉乳头状瘤之间高度可能存在关联，因此该病被认定为职业病。激光烟雾的传染性：在切除乳头状瘤和尖锐湿疣后，已多次在激光烟雾中检测到HPV-DNA。目前尚未确切证明这些颗粒具有传染性。
按照推荐的防护措施，外科医生和护士的潜在感染风险估计非常低。由于妇科手术中的组织块大得多，且采用开放式手术时激光烟雾更容易逸入室内空气中，因此妇科手术中的暴露风险似乎高于耳鼻喉科手术。
