Waites Ken B, Crabb Donna M, Duffy Lynn B
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA.
Antimicrob Agents Chemother. 2003 Dec;47(12):3973-5. doi: 10.1128/AAC.47.12.3973-3975.2003.
We determined in vitro susceptibilities for ABT-492 and other antimicrobials against Mycoplasma pneumoniae, Mycoplasma fermentans, Mycoplasma hominis, and Ureaplasma species. ABT-492 MICs were < or =1 microg/ml, and the agent was bactericidal against selected isolates of M. pneumoniae and M. hominis. ABT-492 has potential for treatment of infections due to these microorganisms.
我们测定了ABT - 492及其他抗菌药物对肺炎支原体、发酵支原体、人型支原体和脲原体属的体外敏感性。ABT - 492的最低抑菌浓度(MIC)≤1微克/毫升,并且该药物对选定的肺炎支原体和人型支原体分离株具有杀菌作用。ABT - 492具有治疗这些微生物所致感染的潜力。