• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

阿奇霉素、克拉霉素、红霉素和洛美沙星对肺炎支原体、人型支原体和解脲脲原体的体外活性比较

Comparative in vitro activity of azithromycin, clarithromycin, erythromycin and lomefloxacin against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum.

作者信息

Renaudin H, Bébéar C

机构信息

Laboratoire de Bactériologie, Hôpital Pellegrin, Bordeaux, France.

出版信息

Eur J Clin Microbiol Infect Dis. 1990 Nov;9(11):838-41. doi: 10.1007/BF01967388.

DOI:10.1007/BF01967388
PMID:1964899
Abstract

The in vitro activity of three macrolides, azithromycin, clarithromycin and erythromycin and a new fluoroquinolone, lomefloxacin, against pathogenic mycoplasma (16 to 18 strains of Mycoplasma pneumoniae, 41 to 77 strains of Mycoplasma hominis, 65 to 104 strains of Ureaplasma urealyticum) was compared. The three macrolides were highly active against Mycoplasma pneumoniae. Clarithromycin was the most active macrolide against Ureaplasma urealyticum whereas azithromycin was somewhat more active than erythromycin against Mycoplasma hominis. Lomefloxacin was moderately active against all three mycoplasma species.

摘要

比较了三种大环内酯类药物（阿奇霉素、克拉霉素和红霉素）以及一种新型氟喹诺酮类药物洛美沙星对致病性支原体（16至18株肺炎支原体、41至77株人型支原体、65至104株解脲脲原体）的体外活性。这三种大环内酯类药物对肺炎支原体具有高度活性。克拉霉素是对解脲脲原体活性最强的大环内酯类药物，而阿奇霉素对人型支原体的活性略高于红霉素。洛美沙星对所有三种支原体均具有中等活性。

相似文献

1
Comparative in vitro activity of azithromycin, clarithromycin, erythromycin and lomefloxacin against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum.阿奇霉素、克拉霉素、红霉素和洛美沙星对肺炎支原体、人型支原体和解脲脲原体的体外活性比较
Eur J Clin Microbiol Infect Dis. 1990 Nov;9(11):838-41. doi: 10.1007/BF01967388.
2
In vitro susceptibilities of mycoplasmas and ureaplasmas to new macrolides and aryl-fluoroquinolones.支原体和脲原体对新型大环内酯类药物及芳基氟喹诺酮类药物的体外敏感性
Antimicrob Agents Chemother. 1988 Oct;32(10):1500-2. doi: 10.1128/AAC.32.10.1500.
3
In vitro comparison of the activity of doxycycline, tetracycline, erythromycin and a new macrolide, CP 62993, against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum.强力霉素、四环素、红霉素及一种新型大环内酯类抗生素CP 62993对肺炎支原体、人型支原体和解脲脲原体活性的体外比较
Scand J Infect Dis Suppl. 1988;53:12-7.
4
The in vitro activity of some 14-, 15- and 16- membered macrolides against Staphylococcus spp., Legionella spp., Mycoplasma spp. and Ureaplasma urealyticum.一些14元、15元和16元大环内酯类药物对葡萄球菌属、军团菌属、支原体属和溶脲脲原体的体外活性。
Drugs Exp Clin Res. 1991;17(2):91-9.
5
In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.肺炎支原体、人型支原体和解脲脲原体对司帕沙星和PD 127391的体外敏感性
Antimicrob Agents Chemother. 1991 Jun;35(6):1181-5. doi: 10.1128/AAC.35.6.1181.
6
In-vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum to clinafloxacin, PD 131628, ciprofloxacin and comparator drugs.肺炎支原体、人型支原体和解脲脲原体对克林沙星、PD 131628、环丙沙星及对照药物的体外敏感性。
J Antimicrob Chemother. 1997 Aug;40(2):308-9. doi: 10.1093/jac/40.2.308.
7
Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines, and quinolones.人型支原体、肺炎支原体和解脲脲原体对GAR-936、达福普汀、地红霉素、依维霉素、加替沙星、利奈唑胺、莫西沙星、奎奴普丁-达福普汀和泰利霉素的敏感性与其对参考大环内酯类、四环素类和喹诺酮类药物的敏感性比较。
Antimicrob Agents Chemother. 2001 Sep;45(9):2604-8. doi: 10.1128/AAC.45.9.2604-2608.2001.
8
In vitro activity of lomefloxacin against Chlamydia trachomatis, Neisseria gonorrhoeae, Haemophilus ducreyi, Mycoplasma hominis, and Ureaplasma urealyticum.洛美沙星对沙眼衣原体、淋病奈瑟菌、杜克嗜血杆菌、人型支原体和解脲脲原体的体外活性。
Diagn Microbiol Infect Dis. 1989 May-Jun;12(3 Suppl):83S-86S. doi: 10.1016/0732-8893(89)90071-0.
9
Comparative in vitro susceptibilities and bactericidal activities of investigational fluoroquinolone ABT-492 and other antimicrobial agents against human mycoplasmas and ureaplasmas.新型氟喹诺酮类药物ABT-492与其他抗菌药物对人型支原体和脲原体的体外敏感性及杀菌活性比较
Antimicrob Agents Chemother. 2003 Dec;47(12):3973-5. doi: 10.1128/AAC.47.12.3973-3975.2003.
10
Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma spp.吉米沙星、新型喹诺酮类、大环内酯类、四环素类及克林霉素对支原体属的相对效价
J Antimicrob Chemother. 2000 Apr;45 Suppl 1:29-33. doi: 10.1093/jac/45.suppl_3.29.

引用本文的文献

1
A phase II, multicenter, nonblinded, randomized controlled trial for evaluating protective effects of ABPC/SBT plus, azithromycin versus erythromycin, in pregnant women with pPROM occurring at <28 weeks of gestation on the development of BPD in neonates: Study protocol.一项 II 期、多中心、非盲、随机对照试验，旨在评估在妊娠 28 周前发生 pPROM 的孕妇中，ABPC/SBT 加阿奇霉素与红霉素相比对新生儿 BPD 发育的保护作用：研究方案。
PLoS One. 2024 Jul 9;19(7):e0304705. doi: 10.1371/journal.pone.0304705. eCollection 2024.
2
SARS-CoV-2, Zika viruses and mycoplasma: Structure, pathogenesis and some treatment options in these emerging viral and bacterial infectious diseases.严重急性呼吸综合征冠状病毒 2 型、寨卡病毒和支原体：这些新发病毒性和细菌性传染病的结构、发病机制及一些治疗选择。
Biochim Biophys Acta Mol Basis Dis. 2021 Dec 1;1867(12):166264. doi: 10.1016/j.bbadis.2021.166264. Epub 2021 Sep 3.
3

本文引用的文献

1
[Comparative activity of minocycline and doxycycline on mycoplasmas pathogenic for man].[米诺环素和多西环素对人类致病性支原体的比较活性]
Pathol Biol (Paris). 1985 Jun;33(5 Pt 2):577-80.
2
In vitro activity of azithromycin and erythromycin against organisms associated with bacterial vaginosis and chancroid.
Eur J Clin Microbiol Infect Dis. 1988 Aug;7(4):551-3. doi: 10.1007/BF01962614.
3
[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].新型喹诺酮类药物对人致病性支原体的体外活性
Intra-Amniotic Infection with Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment with Clarithromycin.解脲支原体感染可导致早产和新生儿死亡，克拉霉素治疗可预防。
mBio. 2020 Jun 23;11(3):e00797-20. doi: 10.1128/mBio.00797-20.
4
Neonatal Ureaplasma urealyticum colonization increases pulmonary and cerebral morbidity despite treatment with macrolide antibiotics.尽管使用了大环内酯类抗生素治疗，但新生儿解脲脲原体定植仍会增加肺部和脑部发病率。
Infection. 2016 Jun;44(3):323-7. doi: 10.1007/s15010-015-0858-7. Epub 2015 Oct 30.
5
Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization.多剂量静脉注射阿奇霉素在有脲原体呼吸道定植风险的早产儿中的药代动力学、微生物反应及肺部转归
Antimicrob Agents Chemother. 2015 Jan;59(1):570-8. doi: 10.1128/AAC.03951-14. Epub 2014 Nov 10.
6
Ureaplasma species: role in neonatal morbidities and outcomes.解脲脲原体属：在新生儿发病机制及结局中的作用。
Arch Dis Child Fetal Neonatal Ed. 2014 Jan;99(1):F87-92. doi: 10.1136/archdischild-2012-303351. Epub 2013 Aug 19.
7
Prevalence, molecular diagnosis and treatment of Mycoplasma conjunctivae isolated from infectious keratoconjunctivitis affected Lohi sheep maintained at Livestock Experiment Station, Bahadurnagar, Okara, Pakistan.从巴基斯坦奥卡拉巴哈杜尔纳加尔畜牧实验站感染性角膜结膜炎的洛希绵羊中分离出的结膜支原体的患病率、分子诊断和治疗
Trop Anim Health Prod. 2013 Mar;45(3):737-42. doi: 10.1007/s11250-012-0282-2. Epub 2012 Nov 8.
8
Role of biofilm formation in Ureaplasma antibiotic susceptibility and development of bronchopulmonary dysplasia in preterm neonates.生物膜形成在解脲脲原体抗生素敏感性和早产儿支气管肺发育不良发展中的作用。
Pediatr Infect Dis J. 2013 Apr;32(4):394-8. doi: 10.1097/INF.0b013e3182791ae0.
9
Pharmacokinetics, safety, and biologic effects of azithromycin in extremely preterm infants at risk for ureaplasma colonization and bronchopulmonary dysplasia.阿奇霉素治疗极早产儿解脲脲原体定植及支气管肺发育不良的药代动力学、安全性及生物学效应
J Clin Pharmacol. 2011 Sep;51(9):1264-75. doi: 10.1177/0091270010382021. Epub 2010 Nov 23.
10
Ureaplasma species: role in diseases of prematurity.脲原体属：在早产儿疾病中的作用。
Clin Perinatol. 2010 Jun;37(2):393-409. doi: 10.1016/j.clp.2009.12.003.
Pathol Biol (Paris). 1988 May;36(5):496-9.
4
In vitro susceptibilities of mycoplasmas and ureaplasmas to new macrolides and aryl-fluoroquinolones.支原体和脲原体对新型大环内酯类药物及芳基氟喹诺酮类药物的体外敏感性
Antimicrob Agents Chemother. 1988 Oct;32(10):1500-2. doi: 10.1128/AAC.32.10.1500.
5
In vitro activity of A-56268 (TE-031), a new macrolide, compared with that of erythromycin and clindamycin against selected gram-positive and gram-negative organisms.新型大环内酯类药物A-56268（TE-031）与红霉素和克林霉素相比，对所选革兰氏阳性菌和革兰氏阴性菌的体外活性。
Antimicrob Agents Chemother. 1987 Feb;31(2):328-30. doi: 10.1128/AAC.31.2.328.
6
In vitro comparison of the activity of doxycycline, tetracycline, erythromycin and a new macrolide, CP 62993, against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum.强力霉素、四环素、红霉素及一种新型大环内酯类抗生素CP 62993对肺炎支原体、人型支原体和解脲脲原体活性的体外比较
Scand J Infect Dis Suppl. 1988;53:12-7.
7
Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method.采用琼脂稀释法测定生殖支原体对新型喹诺酮类药物的敏感性。
Antimicrob Agents Chemother. 1989 Jan;33(1):103-7. doi: 10.1128/AAC.33.1.103.
8
Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin.
Diagn Microbiol Infect Dis. 1989 Sep-Oct;12(5):433-5. doi: 10.1016/0732-8893(89)90115-6.
9
[Methods of studying mycoplasma infections].
Ann Biol Clin (Paris). 1989;47(7):415-20.