Verweij Jaco J, Oostvogel Fieke, Brienen Eric A T, Nang-Beifubah Alexis, Ziem Juventus, Polderman Anton M
Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands.
Trop Med Int Health. 2003 Dec;8(12):1153-6. doi: 10.1046/j.1360-2276.2003.01145.x.
Since the redescription of the potentially invasive Entamoeba histolytica, separating it from the morphologically identical non-invasive Entamoeba dispar, there is a need for the reassessment of epidemiological data on amoebiasis. In this context we conducted a descriptive survey on the presence of E. histolytica and E. dispar in a rural area in northern Ghana. We found a high prevalence (39.8%) of the E. histolytica/E. dispar complex with microscopy, but E. histolytica and E. dispar-specific DNA amplification using real-time polymerase chain reaction identified only one E. histolytica case and revealed a considerably higher prevalence of E. dispar (82.8%).
自从重新描述了具有潜在侵袭性的溶组织内阿米巴,并将其与形态相同的非侵袭性迪斯帕内阿米巴区分开来后,有必要重新评估阿米巴病的流行病学数据。在此背景下,我们对加纳北部一个农村地区的溶组织内阿米巴和迪斯帕内阿米巴的存在情况进行了描述性调查。通过显微镜检查,我们发现溶组织内阿米巴/迪斯帕内阿米巴复合体的患病率很高(39.8%),但使用实时聚合酶链反应进行的溶组织内阿米巴和迪斯帕内阿米巴特异性DNA扩增仅鉴定出1例溶组织内阿米巴病例,并显示迪斯帕内阿米巴的患病率相当高(82.8%)。