Mashino Tadahiko, Nishikawa Dai, Takahashi Kyoko, Usui Noriko, Yamori Takao, Seki Masako, Endo Toyoshige, Mochizuki Masataka
Kyoritsu College of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan.
Bioorg Med Chem Lett. 2003 Dec 15;13(24):4395-7. doi: 10.1016/j.bmcl.2003.09.040.
We examined the antibacterial and antiproliferative activities of alkylated C(60)-bis(N,N-dimethylpyrrolidinium iodide) derivatives. The fullerene derivatives inhibited bacteria and cancer cell growth effectively. However, the fullerene derivatives with a long alkyl chain did not show antibacterial activity.
我们研究了烷基化C(60)-双(N,N-二甲基碘化吡咯烷鎓)衍生物的抗菌和抗增殖活性。富勒烯衍生物能有效抑制细菌和癌细胞生长。然而，具有长烷基链的富勒烯衍生物未表现出抗菌活性。
