变应性肉芽肿性血管炎中的双侧视网膜中央动脉阻塞
Bilateral central retinal artery occlusion in Churg-Strauss syndrome.
作者信息
Udono Tetsuo, Abe Toshiaki, Sato Hajime, Tamai Makoto
机构信息
Department of Ophthalmology and Visual Science, Tohoku University Graduate School of Medicine, Miyagi, Japan.
出版信息
Am J Ophthalmol. 2003 Dec;136(6):1181-3. doi: 10.1016/s0002-9394(03)00712-8.
PURPOSE
To describe a rare bilateral central retinal artery occlusion in a patient with Churg-Strauss syndrome.
DESIGN
Observational case report.
METHODS
A 68-year-old Japanese man with Churg-Strauss syndrome developed sudden vision loss in both eyes. Medical history included bronchial asthma, elevated eosinophils, and aortic regurgitation.
RESULT
Central retinal artery occlusion was diagnosed by retinal whitening, a cherry-red spot, and delayed arteriovenous transit time on fluorescein angiography. Corticosteroids, cyclophosphamide, and anticoagulant therapy altered the hypereosinophilia and mononeuritis multiplex, but no visual recovery occurred during the following 2 years.
CONCLUSION
Bilateral central retinal artery occlusion can occur in Churg-Strauss syndrome. Patients with this diagnosis should be carefully followed.
目的
描述1例患有变应性肉芽肿性血管炎（Churg-Strauss综合征）患者罕见的双侧视网膜中央动脉阻塞情况。
设计
观察性病例报告。
方法
一名68岁患有Churg-Strauss综合征的日本男性双眼突然失明。病史包括支气管哮喘、嗜酸性粒细胞增多及主动脉反流。
结果
通过视网膜变白、樱桃红斑以及荧光素血管造影显示的动静脉传输时间延迟诊断为视网膜中央动脉阻塞。皮质类固醇、环磷酰胺及抗凝治疗改善了嗜酸性粒细胞增多及多发性单神经炎，但在接下来的2年中视力未恢复。
结论
Churg-Strauss综合征可发生双侧视网膜中央动脉阻塞。对此诊断的患者应进行密切随访。
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