Sirigu Angela, Daprati Elena, Ciancia Sophie, Giraux Pascal, Nighoghossian Norbert, Posada Andres, Haggard Patrick
Institut des Sciences Cognitives CNRS, 67 Blv Pinel, 69675 Bron, France.
Nat Neurosci. 2004 Jan;7(1):80-4. doi: 10.1038/nn1160. Epub 2003 Nov 30.
A central question in the study of human behavior is the origin of willed action. EEG recordings of surface brain activity from human subjects performing a self-initiated movement show that the subjective experience of wanting to move follows, rather than precedes, the 'readiness potential'--an electrophysiological mark of motor preparation. This raises the issue of how conscious experience of willed action is generated. Here we show that patients with parietal lesions can report when they started moving, but not when they first became aware of their intention to move. This stands in contrast with the performance of cerebellar patients who behaved as normal subjects. We thus propose that when a movement is planned, activity in the parietal cortex, as part of a cortico-cortical sensorimotor processing loop, generates a predictive internal model of the upcoming movement. This model might form the neural correlate of motor awareness.
人类行为研究中的一个核心问题是意志行动的起源。对进行自发运动的人类受试者的大脑表面活动进行脑电图记录显示，想要运动的主观体验是跟随而非先于“准备电位”出现的，“准备电位”是运动准备的一种电生理标志。这就引发了意志行动的意识体验是如何产生的问题。在这里，我们表明，患有顶叶病变的患者能够报告他们何时开始运动，但不能报告他们何时首次意识到自己的运动意图。这与表现正常的小脑患者的情况形成了对比。因此，我们提出，当计划进行一项运动时，作为皮质 - 皮质感觉运动处理回路一部分的顶叶皮质活动会生成即将发生运动的预测性内部模型。这个模型可能构成运动意识的神经关联。
