Hattermann K, Schmitt C, Soike D, Mankertz A
P11 Neue Viren/Xenotranplantation, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany.
Arch Virol. 2003 Dec;148(12):2471-80. doi: 10.1007/s00705-003-0181-y. Epub 2003 Sep 16.
The genome of Duck circovirus (DuCV) is circular and 1996 nts in size. Two major open reading frames were identified, encoding the replicase (V1) and the capsid protein (C1). A stem-loop structure comprising the nonamer 5'-TATTATTAC, conserved in all circo-, nano- and geminiviruses, was found. Unique to DuCV, the region between the 3'-ends of the rep and cap gene contains four repeats of a 44-bp sequence. Phylogenetic analysis shows close relation of DuCV with Goose circovirus and suggests classification of DuCV as a new member of the genus Circovirus of the virus family Circoviridae.
鸭圆环病毒（DuCV）的基因组呈环状，大小为1996个核苷酸。已鉴定出两个主要的开放阅读框，分别编码复制酶（V1）和衣壳蛋白（C1）。发现了一个包含九聚体5'-TATTATTAC的茎环结构，该结构在所有圆环病毒、纳米病毒和双生病毒中都保守。DuCV独有的特点是，rep和cap基因3'端之间的区域包含一个44碱基序列的四个重复。系统发育分析表明DuCV与鹅圆环病毒关系密切，并建议将DuCV归类为圆环病毒科圆环病毒属的一个新成员。
