Mutations in RNAi rescue aberrant chemotaxis of ADAR mutants.
作者信息
Tonkin Leath A, Bass Brenda L
机构信息
Department of Biochemistry and Howard Hughes Medical Institute, University of Utah, 20 North 1900 East, Salt Lake City, UT 84132-3201, USA.
出版信息
Science. 2003 Dec 5;302(5651):1725. doi: 10.1126/science.1091340.
Abstract
摘要
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Widespread occurrence of antisense transcription in the human genome.反义转录在人类基因组中广泛存在。
Nat Biotechnol. 2003 Apr;21(4):379-86. doi: 10.1038/nbt808. Epub 2003 Mar 17.
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EMBO J. 2002 Nov 15;21(22):6025-35. doi: 10.1093/emboj/cdf607.
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The role of RNA editing by ADARs in RNAi.腺苷脱氨酶作用于RNA的RNA编辑在RNA干扰中的作用。
Mol Cell. 2002 Oct;10(4):809-17. doi: 10.1016/s1097-2765(02)00649-4.
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The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans.双链RNA结合蛋白RDE-4与RDE-1、DCR-1和一种DExH盒解旋酶相互作用，以指导秀丽隐杆线虫中的RNA干扰。
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RNA hairpins in noncoding regions of human brain and Caenorhabditis elegans mRNA are edited by adenosine deaminases that act on RNA.人类大脑非编码区域和秀丽隐杆线虫信使核糖核酸中的RNA发夹结构由作用于RNA的腺苷脱氨酶进行编辑。
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