Fava Maurizio
Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
J Clin Psychiatry. 2003;64 Suppl 14:30-4.
Patients with major depressive disorder commonly experience fatigue and cognitive/executive dysfunction. These problems may be symptoms of the depression and persist despite effective antidepressant treatment, or these problems may emerge as adverse effects of some antidepressant treatments. A number of augmentation strategies can be employed to manage fatigue or cognitive/executive dysfunction, but the efficacy of these augmentation strategies must be researched further.
重度抑郁症患者通常会经历疲劳以及认知/执行功能障碍。这些问题可能是抑郁症的症状，即便接受了有效的抗抑郁治疗仍会持续存在；或者这些问题可能是某些抗抑郁治疗的不良反应。可以采用多种增效策略来处理疲劳或认知/执行功能障碍，但这些增效策略的疗效仍需进一步研究。
