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意大利37型脑膜炎奈瑟菌菌株中荚膜置换的首次报告。

First report of capsule replacement among electrophoretic type 37 Neisseria meningitidis strains in Italy.

作者信息

Stefanelli Paola, Fazio Cecilia, Neri Arianna, Sofia Tonino, Mastrantonio Paola

机构信息

Laboratory of Bacteriology and Medical Mycology, Istituto Superiore di Sanitá, Rome, Italy.

出版信息

J Clin Microbiol. 2003 Dec;41(12):5783-6. doi: 10.1128/JCM.41.12.5783-5786.2003.

DOI:10.1128/JCM.41.12.5783-5786.2003
PMID:14662983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC309013/
Abstract

This report describes the C-to-B capsular switching in four Neisseria meningitidis strains belonging to the electrophoretic type 37 (ET-37) complex. In particular, one strain belonged to the new sequence type 1860, which was first detected in the year 2000 in Italy and is now frequently isolated. The presence of switched serogroup B strains deserves special attention if they prove as able to spread as their serogroup C progenitors belonging to the hypervirulent ET-37 complex.

摘要

本报告描述了4株属于电泳型37（ET-37）复合体的脑膜炎奈瑟菌的C群到B群荚膜转换。特别地，其中一株属于新的序列型1860，该序列型于2000年在意大利首次检测到，目前经常被分离出来。如果转换后的B群菌株证明与属于高毒力ET-37复合体的C群祖先菌株一样具有传播能力，那么它们的存在值得特别关注。

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