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致病性念珠菌属中血浆凝固酶的表达

Expression of plasma coagulase among pathogenic Candida species.

作者信息

Rodrigues Acácio Gonçalves, Pina-Vaz Cidália, Costa-de-Oliveira Sofia, Tavares Christina

机构信息

Department of Microbiology, Porto Faculty of Medicine. Institute of Pathology and Molecular Immunology, University of Porto, Porto, Portugal.

出版信息

J Clin Microbiol. 2003 Dec;41(12):5792-3. doi: 10.1128/JCM.41.12.5792-5793.2003.

DOI:10.1128/JCM.41.12.5792-5793.2003
PMID:14662985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC308979/
Abstract

Candida coagulase production was assessed by the classical tube test. All Candida krusei strains were coagulase negative, but most C. albicans and C. tropicalis strains can produce coagulase. Some strains agglutinated the Pastorex Staph-Plus reagent, probably because of antigen similarities to coagulase produced by Staphylococcus aureus that may cause mistakes in clinical laboratories.

摘要

通过经典试管试验评估念珠菌凝固酶的产生情况。所有克柔念珠菌菌株的凝固酶均为阴性,但大多数白色念珠菌和热带念珠菌菌株可产生凝固酶。一些菌株可使Pastorex Staph-Plus试剂发生凝集,这可能是因为其与金黄色葡萄球菌产生的凝固酶存在抗原相似性,这可能会在临床实验室中导致错误。

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本文引用的文献

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Differential secretion of Sap4-6 proteins in Candida albicans during hyphae formation.白色念珠菌菌丝形成过程中Sap4-6蛋白的差异分泌
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Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs.白色念珠菌的菌丝形成以及Efg1调控的蛋白酶Sap4至Sap6的表达是实质器官侵袭所必需的。
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