Doherty Liam S, Kiely John L, Lawless Geraldine, McNicholas Walter T
Respiratory Sleep Disorders Unit, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Chest. 2003 Dec;124(6):2209-14. doi: 10.1378/chest.124.6.2209.
Continuous positive airway pressure (CPAP) improves daytime sleepiness and quality of life in patients with obstructive sleep apnea syndrome (OSAS). However, few studies have examined the impact of treatment on the quality of life of bed partners of these patients.
We prospectively studied 55 couples in which one person (the patient) had OSAS diagnosed and was subsequently commenced on CPAP therapy; 45 of these couples shared a bed on a regular basis. Both partner and patient completed postal questionnaires immediately prior to CPAP therapy and again after a median of 8 weeks (interquartile range [IQR], 6 to 12 weeks) of therapy at home. Questionnaires consisted of the Epworth sleepiness scale (ESS), the UK Short Form-36 health survey, and the hospital anxiety and depression scale. No intervention or advice was given to the partner of the patient receiving CPAP therapy.
In addition to the expected significant benefits reported by patients receiving CPAP, bed partners also reported significant improvements in ESS scores (median, 4 [IQR, 1 to 8.5] before CPAP; median, 2 [IQR, 1 to 5] during CPAP), in addition to measures of anxiety, role limitation due to physical problems, role limitation due to emotional problems, social functioning, mental health, and energy/vitality (all p < 0.05 by Wilcoxon-signed rank testing).
These data support the hypothesis that partners of patients with OSAS benefit significantly from the CPAP therapy their bed partners receive.
持续气道正压通气（CPAP）可改善阻塞性睡眠呼吸暂停综合征（OSAS）患者的日间嗜睡及生活质量。然而，很少有研究探讨该治疗方法对这些患者床伴生活质量的影响。
我们前瞻性研究了55对夫妇，其中一方（患者）被诊断为OSAS，随后开始接受CPAP治疗；这些夫妇中有45对定期同床共眠。伴侣和患者在CPAP治疗前均通过邮寄方式完成问卷调查，在家接受治疗中位时间8周（四分位间距[IQR]，6至12周）后再次进行问卷调查。问卷包括爱泼沃斯嗜睡量表（ESS）、英国简明健康调查问卷（SF-36）以及医院焦虑抑郁量表。对于接受CPAP治疗患者的伴侣未给予任何干预或建议。
除了接受CPAP治疗的患者报告的预期显著益处外，床伴们也报告了ESS评分显著改善（CPAP治疗前中位数为4[IQR，1至8.5]；CPAP治疗期间中位数为2[IQR，1至5]），此外，在焦虑、因身体问题导致的角色受限、因情感问题导致的角色受限、社会功能、心理健康以及精力/活力等方面也有改善（通过Wilcoxon符号秩检验，所有p<0.05）。
这些数据支持以下假设，即OSAS患者的伴侣从其床伴接受的CPAP治疗中显著获益。
