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类风湿关节炎健康状况变化测量的两种方法比较:健康评估问卷(HAQ)与改良版HAQ。

Comparison of two approaches to measuring change in health status in rheumatoid arthritis: the Health Assessment Questionnaire (HAQ) and modified HAQ.

作者信息

Ziebland S, Fitzpatrick R, Jenkinson C, Mowat A, Mowat A

机构信息

Department of Public Health and Primary Care, University of Oxford, Radcliffe Infirmary, U.K.

出版信息

Ann Rheum Dis. 1992 Nov;51(11):1202-5. doi: 10.1136/ard.51.11.1202.

Abstract

As an alternative to the calculation of change scores for health status questionnaires used in clinical trials or longitudinal studies, transitional questions have been developed for patients to assess changes directly themselves. Here the original Health Assessment Questionnaire (HAQ) is compared with a modified version of the HAQ (MHAQ) which contains transition questions used at follow up. These, together with a set of standard rheumatological tests, were all completed by 100 patients with rheumatoid arthritis on two occasions, three months apart. Change scores were calculated for the HAQ and for the clinical measures and compared with the MHAQ. The results were strikingly in favour of encouraging patients to assess their own degree of change through the use of transition questions in the MHAQ.

摘要

作为临床试验或纵向研究中用于健康状况问卷变化分数计算的替代方法,已开发出过渡性问题供患者直接自行评估变化情况。本文将原始的健康评估问卷(HAQ)与HAQ的修改版(MHAQ)进行比较,MHAQ包含随访时使用的过渡性问题。100名类风湿性关节炎患者分两次完成了这些问题以及一套标准的风湿病学检查,两次间隔三个月。计算了HAQ和临床指标的变化分数,并与MHAQ进行比较。结果显著支持鼓励患者通过使用MHAQ中的过渡性问题来评估自身的变化程度。

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Outcome assessment in clinical trials. Evidence for the sensitivity of a health status measure.
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