Lobbezoo Frank, Visscher Corine M, Naeije Machiel
Department of Oral Function, Academic Centre for Dentistry, Amsterdam (ACTA), Louwesweg 1, 1066 EA, Amsterdam, Netherlands.
Eur J Pain. 2004 Feb;8(1):23-30. doi: 10.1016/S1090-3801(03)00061-2.
This study investigated the relationship between health status (i.e., physical well-being and quality of life), sleep disorders (e.g., insomnia, sleep-related depression and anxiety), and musculoskeletal pain in the craniomandibular and cervical spinal regions. The number of painful body areas below the cervical spine (i.e., widespread pain) was also taken into account. Two questionnaires, viz., the RAND 36-item Health Survey Questionnaire and the Dutch Sleep Disorders Questionnaire (SDQ), were administered to 103 persons who could unequivocally be classified into one of four mutually exclusive groups: No pain, craniomandibular pain (CMP), cervical spinal pain (CSP), and both CMP and CSP. Body drawings were used for the self-report of widespread pain. Multivariate analysis of variance showed effects of gender, group, and widespread pain on the questionnaire scales; not of age. As shown by univariate analysis of variance, men suffered more from sleep apnea than did women. No other gender differences were found. Simple contrast analyses following univariate analyses of the group and widespread pain effects showed that, in general, more questionnaire scales, both of the RAND-36 and of the SDQ, reached statistical significance with an increase in the number of painful areas. It was concluded that both musculoskeletal pain in the trigemino-cervical area and widespread body pain are associated with an increased impairment of health status. Also, sleep disorders are frequently found in patients with chronic pain in the craniomandibular and cervical spinal regions as well as in patients with widespread pain. The more painful areas there are, the likelier it is that sleep disorders are present.
本研究调查了健康状况（即身体健康和生活质量）、睡眠障碍（如失眠、与睡眠相关的抑郁和焦虑）与颅下颌和颈椎区域肌肉骨骼疼痛之间的关系。还考虑了颈椎以下疼痛身体部位的数量（即广泛性疼痛）。向103人发放了两份问卷，即兰德36项健康调查问卷和荷兰睡眠障碍问卷（SDQ），这些人可以明确地被分为四个相互排斥的组之一：无疼痛、颅下颌疼痛（CMP）、颈椎疼痛（CSP）以及CMP和CSP两者。使用身体绘图来自我报告广泛性疼痛。多变量方差分析显示性别、组和广泛性疼痛对问卷量表有影响；年龄则无影响。单变量方差分析表明，男性比女性更容易患睡眠呼吸暂停。未发现其他性别差异。在对组和广泛性疼痛效应进行单变量分析后的简单对比分析表明，一般来说，随着疼痛区域数量的增加，兰德36项问卷和SDQ的更多问卷量表达到统计学显著性。研究得出结论，三叉神经 - 颈部区域的肌肉骨骼疼痛和全身性广泛性疼痛均与健康状况受损增加有关。此外，在颅下颌和颈椎区域患有慢性疼痛的患者以及患有广泛性疼痛的患者中经常发现睡眠障碍。疼痛区域越多，出现睡眠障碍的可能性就越大。
