视网膜电图（ERG）反应的发展：正常受试者的国际临床视觉电生理学会（ISCEV）标准视杆细胞、最大反应和视锥细胞反应
Development of ERG responses: the ISCEV rod, maximal and cone responses in normal subjects.
作者信息
Fulton Anne B, Hansen Ronald M, Westall Carol A
机构信息
Department of Ophthalmology, The Children's Hospital, Boston, MA 02115, USA.
出版信息
Doc Ophthalmol. 2003 Nov;107(3):235-41. doi: 10.1023/b:doop.0000005332.88367.b8.
PURPOSE
Summarize ISCEV ERG responses from normal infants and children.
METHODS
The amplitudes and implicit times of the ISCEV rod, maximal dark-adapted and cone responses from a total of 409 normal infants (n = 128), children and adult controls were compiled. The subjects, aged 1 week to 52 years, were divided into seven age groups, including four in infancy (< 52 weeks). The response parameters for each age group were summarized as percentiles.
RESULTS
In each ISCEV condition, the youngest infants (1-5 weeks) had significantly smaller amplitudes and longer implicit times than adults. Amplitude increased and implicit time decreased systematically with age.
CONCLUSIONS
The developmental changes in ERG responses are significant. The medians and ranges herein provide provisional norms against which the ERG responses from pediatric patients can be compared.
目的
总结正常婴幼儿和儿童的国际临床视觉电生理学会（ISCEV）视网膜电图（ERG）反应。
方法
汇总了总共409名正常婴儿（n = 128）、儿童及成人对照的ISCEV视杆细胞、最大暗适应反应和视锥细胞反应的振幅及潜伏时间。受试者年龄为1周龄至52岁，分为七个年龄组，其中包括四个婴儿期组（<52周）。每个年龄组的反应参数汇总为百分位数。
结果
在每种ISCEV条件下，最年幼的婴儿（1 - 5周）的振幅明显小于成人，潜伏时间明显长于成人。振幅随年龄系统性增加，潜伏时间随年龄系统性减少。
结论
ERG反应的发育变化显著。本文中的中位数和范围提供了临时标准，可用于比较儿科患者的ERG反应。
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