Pettigrew Melinda M, Gent Janneane F, Triche Elizabeth W, Belanger Kathleen D, Bracken Michael B, Leaderer Brian P
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven Connecticut 06520-8034, USA.
Epidemiology. 2004 Jan;15(1):13-20. doi: 10.1097/01.ede.0000101292.41006.2e.
This prospective study investigated the association of exposure to indoor secondary heating sources with otitis media and recurrent otitis media risk in infants.
We enrolled mothers living in nonsmoking households and delivering babies between 1993 and 1996 in 12 Connecticut and Virginia hospitals. Biweekly telephone interviews during the first year of life assessed diagnoses from doctors' office visits and use of secondary home heating sources, air conditioner use, and day care. Otitis media episodes separated by more than 21 days were considered to be unique episodes. Recurrent otitis media was defined as 4 or more episodes of otitis media. Repeated-measures logistic regression modeling evaluated the association of kerosene heater, fireplace, or wood stove use with otitis media episodes while controlling for potential confounders. Logistic regression evaluated the relation of these secondary heating sources with recurrent otitis media.
None of the secondary heating sources were associated with otitis media or with recurrent otitis media. Otitis media was associated with day care, the winter heating season, birth in the fall, white race, additional children in the home, and a maternal history of allergies in multivariate models. Recurrent otitis media was associated with day care, birth in the fall, white race, and a maternal history of allergies or asthma.
We found no evidence that the intermittent use of secondary home heating sources increases the risk of otitis media or recurrent otitis media. This study confirms earlier findings regarding the importance of day care with respect to otitis media risk.
这项前瞻性研究调查了婴儿接触室内二次加热源与中耳炎及复发性中耳炎风险之间的关联。
我们招募了居住在无烟家庭且于1993年至1996年间在康涅狄格州和弗吉尼亚州12家医院分娩的母亲。在婴儿出生后的第一年，每两周进行一次电话访谈，评估医生门诊诊断情况、二次家庭加热源的使用、空调使用情况以及日托情况。间隔超过21天的中耳炎发作被视为独立发作。复发性中耳炎定义为中耳炎发作4次或更多次。重复测量逻辑回归模型在控制潜在混杂因素的同时，评估煤油取暖器、壁炉或木炉的使用与中耳炎发作之间的关联。逻辑回归评估这些二次加热源与复发性中耳炎之间的关系。
二次加热源均与中耳炎或复发性中耳炎无关。在多变量模型中，中耳炎与日托、冬季供暖季节、秋季出生、白人种族、家中有其他孩子以及母亲有过敏史有关。复发性中耳炎与日托、秋季出生、白人种族以及母亲有过敏或哮喘病史有关。
我们没有发现证据表明间歇性使用二次家庭加热源会增加中耳炎或复发性中耳炎的风险。本研究证实了早期关于日托对中耳炎风险重要性的研究结果。
