细菌蛋白毒素引起的细胞损伤与死亡。
Cell injury and death caused by bacterial protein toxins.
作者信息
Donelli G, Fiorentini C
机构信息
Department of Ultrastructures, Istituto Superiore di Sanità, Rome, Italy.
出版信息
Toxicol Lett. 1992 Dec;64-65 Spec No:695-9. doi: 10.1016/0378-4274(92)90249-j.
PMID:1471224
Abstract
Bacterial protein toxins, such as Clostridium difficile toxin A and the Escherichia coli cytotoxic necrotizing factor 1 are known to exert their cytotoxic action via a modification of some cytoskeletal components. The changes in actin organization caused by these toxins appear to be the primary events in the mechanism leading to cell death.
摘要
已知细菌蛋白毒素，如艰难梭菌毒素A和大肠杆菌细胞毒性坏死因子1，通过修饰某些细胞骨架成分发挥其细胞毒性作用。这些毒素引起的肌动蛋白组织变化似乎是导致细胞死亡机制中的主要事件。
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