Yokoyama Tadashi, Egami K, Miyamoto M, Watanabe H, Hasegawa H, Iida S, Suzuki S, Nakamura Y, Okawa K, Hagiwara N, Takashima Y, Yoshioka M, Tajiri T, Onda M
Department of Surgery, Nippon Medical School, Tama-Nagayama Hospital, 1-7-1 Nagayama, Tama, Tokyo 206-8512, Japan.
J Hepatobiliary Pancreat Surg. 2003;10(6):425-7. doi: 10.1007/s00534-002-0830-7.
BACKGROUND/PURPOSE: Radiofrequency ablation (RFA) and microwave coagulation therapy (MCT) have been gaining acceptance as a standard method in the management strategy of liver cancer, for reasons of minimally invasive techniques and effective results. We present our experience of RFA and MCT in patients with liver cancer, and analyze retrospectively the advantages and disadvantages of both of the percutaneous and laparoscopic approaches.
Thirty-two consecutive patients (23 men and 9 women) with 19 hepatocellular carcinomas (HCC), 12 metastatic liver cancers, and recurrent cholangiocellular carcinoma (CCC), were enrolled in this study. Out of these 32 patients, as a prior laparotomy, 19 underwent hepatectomy, colectomy, gastrectomy or cholecystectomy, and 15 were treated with the laparoscopic approach, 17 treated with the percutaneous approach, and 2 treated with the combined approach of those two. All of these procedures were carried out under general anesthesia with ultrasound guidance. Seven and 30 days after these procedures, an assessment helical computed tomography was done.
No sign of the residual tissues was noted in all patients except only one case.
The percutaneous approach was thought to be a more practical and less invasive method regardless previous laparotomy. For the laparoscopic approach, tumors located at the hepatic surface or margin were preferable candidates.
背景/目的:由于具有微创技术和有效结果的特点,射频消融(RFA)和微波凝固治疗(MCT)已逐渐成为肝癌治疗策略中的标准方法。我们介绍了我们在肝癌患者中应用RFA和MCT的经验,并回顾性分析了经皮和腹腔镜两种途径的优缺点。
本研究纳入了32例连续患者(23例男性和9例女性),其中有19例肝细胞癌(HCC)、12例转移性肝癌和复发性胆管细胞癌(CCC)。在这32例患者中,19例曾接受过肝切除术、结肠切除术、胃切除术或胆囊切除术,15例采用腹腔镜途径治疗,17例采用经皮途径治疗,2例采用两种途径联合治疗。所有这些手术均在全身麻醉和超声引导下进行。术后7天和30天进行螺旋CT评估。
除1例患者外,所有患者均未发现残留组织迹象。
无论之前是否接受过剖腹手术,经皮途径被认为是一种更实用、侵入性更小的方法。对于腹腔镜途径,位于肝表面或边缘的肿瘤是更合适的候选对象。