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[克罗恩病伴局灶性肺部病变]

[Crohn's disease associated with focal pulmonare lesion].

作者信息

Tagle Martín, Barriga José, Piñeiro Andrés

机构信息

UPCH, Lima, Peru.

出版信息

Rev Gastroenterol Peru. 2003 Oct-Dec;23(4):293-6.

PMID:14716424
Abstract

40 year-old male recently diagnosed with Crohn's disease. A routine chest X ray showed a round, well defined opacity in right lung field. A chest CT scan confirmed the finding and also described bronchiectasis. Patient had no respiratory symptoms. He was prescribed with oral sulfasalazine and corticosteroids with rapid improvement of intestinal symptoms as well as resolution of the pulmonary opacity. We describe the clinical presentation of a male newly diagnosed with Crohn's disease who was found to have an asymptomatic pulmonary lesion on imaging studies. Pulmonary complications have been previously described in inflamatory bowel disease being more common in ulcerative colitis than in Crohn's disease; these can involve the lung parenchyma, the tracheobronchial tree, and the pleura. The true prevalence and etiology of these lesions is currently unknown and are not necessarily associated with bowel disease activity. Abnormal pulmonary functions test have been reported during inflammatory bowel disease exacerbations, and although pulmonary findings can present with a variety of symptoms, subclinical presentations have also been described. Pulmonary manifestations are usually steoid-responsive, as was the case in our patients.

摘要

一名40岁男性最近被诊断为克罗恩病。常规胸部X线检查显示右肺野有一个圆形、边界清晰的不透光区。胸部CT扫描证实了这一发现,并显示有支气管扩张。患者无呼吸道症状。他接受了口服柳氮磺胺吡啶和皮质类固醇治疗,肠道症状迅速改善,肺部不透光区也消失了。我们描述了一名新诊断为克罗恩病的男性患者的临床表现,该患者在影像学检查中发现有无症状肺部病变。先前已描述过炎症性肠病的肺部并发症,在溃疡性结肠炎中比在克罗恩病中更常见;这些并发症可累及肺实质、气管支气管树和胸膜。这些病变的真实患病率和病因目前尚不清楚,且不一定与肠道疾病活动相关。炎症性肠病发作期间曾报告肺功能测试异常,尽管肺部表现可伴有多种症状,但也有亚临床表现的描述。肺部表现通常对类固醇有反应,我们的患者就是如此。

相似文献

1
[Crohn's disease associated with focal pulmonare lesion].[克罗恩病伴局灶性肺部病变]
Rev Gastroenterol Peru. 2003 Oct-Dec;23(4):293-6.
2
[Inflammatory bowel disease and lung].[炎症性肠病与肺]
Tuberk Toraks. 2006;54(3):292-8.
3
Paediatric inflammatory bowel disease in New Zealand.新西兰的儿童炎症性肠病
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Dig Liver Dis. 2005 Jun;37(6):407-17. doi: 10.1016/j.dld.2004.12.013.
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[Association between membranous glomerulonephritis and Crohn's disease].膜性肾小球肾炎与克罗恩病之间的关联
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7
[Pericarditis in chronic inflammatory bowel disease: underlying disease or side effects of therapy? Clinical problem solving].
Schweiz Med Wochenschr. 1996 Dec 14;126(50):2184-90.
8
[Vulvar Crohn disease: 3 cases].[外阴克罗恩病:3例]
Ann Dermatol Venereol. 1997;124(9):629-32.
9
A case of linear IgA disease occurring in a patient with colonic Crohn's disease.1例结肠克罗恩病患者发生线状IgA病。
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10
CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies.荷兰家族性和散发性炎症性肠病中的CARD15突变及欧洲研究综述。
Eur J Gastroenterol Hepatol. 2007 Jun;19(6):449-59. doi: 10.1097/01.meg.0000236887.44214.6a.

引用本文的文献

1
Pulmonary manifestations of Crohn's disease.克罗恩病的肺部表现。
World J Gastroenterol. 2014 Jan 7;20(1):133-41. doi: 10.3748/wjg.v20.i1.133.
2
Tracheobronchial nodules and pulmonary infiltrates in a patient with Crohn's disease.克罗恩病患者的气管支气管结节和肺部浸润。
World J Gastroenterol. 2012 Oct 21;18(39):5653-7. doi: 10.3748/wjg.v18.i39.5653.