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天花疫苗接种后的流式细胞术及T细胞反应监测

Flow cytometry and T-cell response monitoring after smallpox vaccination.

作者信息

Poccia Fabrizio, Gioia Cristiana, Montesano Carla, Martini Federico, Horejsh Douglas, Castilletti Concetta, Pucillo Leopoldo paolo, Capobianchi Maria Rosaria, Ippolito Giuseppe

机构信息

National Institute for Infectious Diseases "Lazzaro Spallanzani," Rome, Italy.

出版信息

Emerg Infect Dis. 2003 Nov;9(11):1468-70. doi: 10.3201/eid0911.030349.

DOI:10.3201/eid0911.030349
PMID:14718095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3035552/
Abstract

Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When the high similarity between the orthopoxviruses is considered, this rapid assay that uses vaccinia antigens could identify recently exposures.

摘要

由于生物恐怖主义或生物战导致的正痘病毒人畜共患病或天花存在流行传播的风险。通过流式细胞术监测T细胞反应，我们观察到近期接种天花疫苗后的回忆反应。考虑到正痘病毒之间的高度相似性，这种使用痘苗抗原的快速检测方法可以识别近期的暴露情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3035552/2544aad38d1e/03-0349-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3035552/2544aad38d1e/03-0349-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3035552/2544aad38d1e/03-0349-F.jpg

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本文引用的文献

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