Verschoor Ernst J, Fagrouch Zahra, Bontjer Ilja, Niphuis Henk, Heeney Jonathan L
Department of Virology, Biomedical Primate Research Centre (BPRC), PO Box 3306, 2206 GH Rijswijk, The Netherlands.
J Gen Virol. 2004 Jan;85(Pt 1):21-24. doi: 10.1099/vir.0.19427-0.
A novel simian immunodeficiency virus (SIV) was characterized from a Schmidt's guenon (Cercopithecus ascanius schmidti), which was housed in a local zoo. The virus infection was detected during a routine serological screening for antibodies that were cross-reactive with SIVmac antigens. Infection with an immunodeficiency virus was confirmed using an INNO-LIA HIV Confirmation assay. Using DNA isolated from a blot clot, a 1895 nt partial pol sequence was amplified and sequenced. Phylogenetic analysis showed that this virus, designated SIVschm, shares a distant relationship with SIVgsn, isolated from greater spot-nosed monkeys, and is one of the most divergent SIVs identified to date.
一种新型猿猴免疫缺陷病毒（SIV）是从一只饲养在当地动物园的施密特长尾猴（Cercopithecus ascanius schmidti）中鉴定出来的。该病毒感染是在对与SIVmac抗原发生交叉反应的抗体进行常规血清学筛查时检测到的。使用INNO-LIA HIV确认试验确认了免疫缺陷病毒感染。利用从印迹凝块中分离的DNA，扩增并测序了一段1895 nt的部分pol序列。系统发育分析表明，这种被命名为SIVschm的病毒与从大白鼻猴中分离出的SIVgsn关系较远，是迄今为止鉴定出的最具分歧性的SIV之一。
