Köhler U, Taubert G, Bilek K, Nenning A
Department of Gynecology and Obstetrics, University of Leipzig, Federal Republic of Germany.
Arch Gynecol Obstet. 1992;252(2):93-7. doi: 10.1007/BF02389634.
We made a prospective cytophotometric study of 48 cases of endometrial carcinoma. Thirty-two (66.7%) of the cases had diploid DNA content and the proportion of non-diploid tumors increased with the staging of tumors, lack of differentiation and depth of myometrial invasion. DNA content (AE), DNA malignancy grade (DNA-MG) and 5c exceeding rate were statistically significant in relation to the clinical course of the disease and the histological grade of differentiation. DNA parameters appear to be especially suitable for the objective assessment of malignancy.
我们对48例子宫内膜癌患者进行了前瞻性细胞光度学研究。其中32例(66.7%)病例的DNA含量为二倍体,非二倍体肿瘤的比例随着肿瘤分期、分化程度的降低以及肌层浸润深度的增加而升高。DNA含量(AE)、DNA恶性度分级(DNA-MG)和5c超标率在疾病临床进程和组织学分化分级方面具有统计学意义。DNA参数似乎特别适合于对恶性程度进行客观评估。