Metyas Samy K, Lum Christopher A, Raza Anwar S, Vaysburd Marina, Forrester Deborah M, Quismorio Francisco P
Division of Rheumatology and Immunology, Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles County/USC Medical Center, 2015 Zonal Avenue, Los Angeles, CA 90033, USA.
J Rheumatol. 2003 Dec;30(12):2713-5.
Metastatic spread of malignancy to the joints is rare and only a few cases of solid tumors have been reported. We describe a patient with inflammatory arthritis of the knee and ankle secondary to metastatic gastric adenocarcinoma to the joints and bone diagnosed by synovianalysis. Arthritis secondary to metastatic cancer is a poor prognostic sign. The diagnosis is based on a strong clinical suspicion, magnetic resonance imaging, and joint fluid cytology or synovial biopsy.
恶性肿瘤转移至关节的情况较为罕见，仅有少数实体瘤病例被报道。我们描述了一名患者，其膝关节和踝关节出现炎症性关节炎，继发于胃腺癌转移至关节和骨骼，通过滑膜分析得以诊断。转移性癌症继发的关节炎是预后不良的征兆。诊断基于强烈的临床怀疑、磁共振成像以及关节液细胞学检查或滑膜活检。
