Guillon Michel, Maissa Cecile, Pouliquen Pascale, Delval Laurent
Optometric Technology Group Ltd., 42 Vauxhall Bridge Road, London SW1V 2RX, UK.
Eye Contact Lens. 2004 Jan;30(1):34-9. doi: 10.1097/01.ICL.0000101489.13687.9A.
To show that the use of povidone 2% preservative-free lubricating eyedrops reduces computer visual syndrome in contact lens wearers and to identify the best eyedrop instillation protocols.
The test product was FILMABAK a CE-marked nonpreserved lubricant, povidone 2% delivered by the ABAK system. Three dispensing modalities were evaluated during contact lens wear and computer use: hourly instillation, symptom-related instillation, and patient's own instillation.
During sustained computer use, a decrease in symptoms associated with the use of povidone 2% was statistically and clinically significant. However, the symptoms were not fully eliminated by the use of the test eyedrop. The three instillation routines achieved similar beneficial effects. No significant changes in ocular tissue response were observed, and the staining recorded after sustained computer use remained low. The use of povidone 2% preservative-free lubricating eyedrops under any of the three instillation modalities tested was also associated with a slight improvement in dynamic visual acuity.
The use of povidone 2% preservative-free eyedrops was associated with an improvement in symptoms during sustained computer use. Any of the three instillation modalities decreased symptoms of ocular tiredness, dryness, and difficulty of focus; maintained an unchanged corneal surface; and improved dynamic visual acuity. Therefore, the most patient-friendly modality (patient's own instillation modality from symptom onset) could be recommended to contact lens wearers with computer visual syndrome.
证明使用不含防腐剂的2%聚维酮润滑眼药水可减轻隐形眼镜佩戴者的计算机视觉综合征,并确定最佳的眼药水滴注方案。
测试产品为FILMABAK,一种通过ABAK系统输送的获得CE标志的无防腐剂润滑剂,2%聚维酮。在佩戴隐形眼镜和使用计算机期间评估了三种滴注方式:每小时滴注、症状相关滴注和患者自行滴注。
在持续使用计算机期间,使用2%聚维酮相关症状的减轻具有统计学和临床意义。然而,使用测试眼药水并未完全消除症状。三种滴注程序产生了相似的有益效果。未观察到眼组织反应有显著变化,持续使用计算机后记录的染色仍较低。在测试的三种滴注方式中的任何一种下使用不含防腐剂的2%聚维酮润滑眼药水,还与动态视力的轻微改善有关。
在持续使用计算机期间,使用不含防腐剂的2%聚维酮眼药水可改善症状。三种滴注方式中的任何一种都可减轻眼疲劳、干涩和聚焦困难的症状;保持角膜表面不变;并提高动态视力。因此,对于患有计算机视觉综合征的隐形眼镜佩戴者,可推荐最方便患者的方式(从症状出现开始患者自行滴注方式)。