Verdun Francis R, Lepori D, Monnin Pascal, Valley Jean-François, Schnyder Pierre, Gudinchet F
University Institute for Applied Radiophysics, Grand-Pré 1, 1007 Lausanne, Switzerland.
Eur Radiol. 2004 May;14(5):835-41. doi: 10.1007/s00330-003-2206-z. Epub 2004 Jan 13.
The aim was to propose a strategy for finding reasonable compromises between image noise and dose as a function of patient weight. Weighted CT dose index (CTDI(w)) was measured on a multidetector-row CT unit using CTDI test objects of 16, 24 and 32 cm in diameter at 80, 100, 120 and 140 kV. These test objects were then scanned in helical mode using a wide range of tube currents and voltages with a reconstructed slice thickness of 5 mm. For each set of acquisition parameter image noise was measured and the Rose model observer was used to test two strategies for proposing a reasonable compromise between dose and low-contrast detection performance: (1) the use of a unique noise level for all test object diameters, and (2) the use of a unique dose efficacy level defined as the noise reduction per unit dose. Published data were used to define four weight classes and an acquisition protocol was proposed for each class. The protocols have been applied in clinical routine for more than one year. CTDI(vol) values of 6.7, 9.4, 15.9 and 24.5 mGy were proposed for the following weight classes: 2.5-5, 5-15, 15-30 and 30-50 kg with image noise levels in the range of 10-15 HU. The proposed method allows patient dose and image noise to be controlled in such a way that dose reduction does not impair the detection of low-contrast lesions. The proposed values correspond to high- quality images and can be reduced if only high-contrast organs are assessed.
目的是提出一种策略,以找到图像噪声和剂量之间合理的折衷方案,该方案是患者体重的函数。在多排探测器CT设备上,使用直径为16、24和32 cm的CTDI测试模体,在80、100、120和140 kV下测量加权CT剂量指数(CTDI(w))。然后,使用一系列管电流和电压以螺旋模式扫描这些测试模体,重建层厚为5 mm。对于每组采集参数,测量图像噪声,并使用罗斯模型观察者测试两种在剂量和低对比度检测性能之间提出合理折衷方案的策略:(1)对所有测试模体直径使用唯一的噪声水平;(2)使用定义为每单位剂量噪声降低量的唯一剂量效能水平。利用已发表的数据定义了四个体重类别,并为每个类别提出了一种采集方案。这些方案已在临床常规中应用了一年多。对于以下体重类别:2.5 - 5、5 - 15、15 - 30和30 - 50 kg,建议的CTDI(vol)值分别为6.7、9.4、15.9和24.5 mGy,图像噪声水平在10 - 15 HU范围内。所提出的方法能够以这样一种方式控制患者剂量和图像噪声,即剂量降低不会损害低对比度病变的检测。所提出的值对应于高质量图像,如果仅评估高对比度器官,则可以降低这些值。