Mel'nichenko E G, Kirsanova M A, Grishkovets V I, Tyshkevich L V, Krivorutchenko Iu L
Crimea State Medical University, Simferopol.
Mikrobiol Z. 2003 Sep-Oct;65(5):8-12.
The antibacterial and antifungal action of saponins Sx1, taurozide H2, taurozide I and their effect on bioluminescent system of photobacteria Photobacterium phosphoreum (Cohn) Ford were investigated. Saponins H2 and I had no antimicrobial effect. Saponin Sx1 possessed antifungal activity in vitro with respect to Candida albicans, C. krusei, C. tropicalis. Saponin Sx1 is less toxic to P. phosphoreum than well-known antiseptics--chlorhexedin and miramistin.
研究了皂苷Sx1、牛磺胆酸H2、牛磺胆酸I的抗菌和抗真菌作用及其对发光细菌费氏弧菌（Cohn）Ford生物发光系统的影响。皂苷H2和I没有抗菌作用。皂苷Sx1在体外对白色念珠菌、克鲁斯念珠菌、热带念珠菌具有抗真菌活性。皂苷Sx1对费氏弧菌的毒性低于知名防腐剂——氯己定和咪拉明。
