Wildman Katherine, Bouvier-Colle Marie-Hélène
Epidemiological Research Unit on Perinatal and Women's Health, Unité 149 INSERM, France.
BJOG. 2004 Feb;111(2):164-9. doi: 10.1046/j.1471-0528.2003.00034.x-i1.
This analysis considers the usefulness of maternal mortality ratio (MMR) as an indicator of obstetric care in the context of low overall maternal mortality. We explore whether variation in the level of MMR among European countries reflects differences in obstetric care.
The data presented in this article were collected as part of the European Concerted Action on Mothers' Mortality and Severe morbidity (MOMS). In this study, a panel of experts followed a protocol to determine cause of death and whether it was pregnancy-related. This analysis uses the expert panel's confirmation of cause of death and obstetric attribution.
All maternal deaths within 11 European countries.
Two hundred and ninety obstetric deaths occuring between 1992 and 1995.
We present the results of a multivariable analysis that controls for cause of death, moment of death, place of death, pregnancy outcome, women's age and nationality.
We test the hypothesis that countries with higher MMR would have proportionally more cases of direct obstetric death due to thromboembolism, hypertension, haemorrhage or infection compared with other countries in the study. We examine timing of death and maternal age to measure whether there are differences between country groups for older mothers.
We find distinct patterns in cause and timing of death and age-specific mortality ratios between countries with different levels of MMR.
Despite low rates of maternal mortality in Europe, between-country differences follow patterns with respect to cause and timing of death and maternal age. In addition to representing an important indicator of health status in a country, differences in MMR among European countries provide insight to where obstetric care plays a role maternal deaths.
本分析探讨在孕产妇总体死亡率较低的情况下,孕产妇死亡率(MMR)作为产科护理指标的有用性。我们探究欧洲国家间MMR水平的差异是否反映了产科护理的差异。
本文所呈现的数据是作为欧洲孕产妇死亡与严重发病情况联合行动(MOMS)的一部分收集的。在本研究中,一个专家小组按照方案确定死亡原因以及是否与妊娠相关。本分析采用专家小组对死亡原因和产科归因的确认。
11个欧洲国家内的所有孕产妇死亡案例。
1992年至1995年间发生的290例产科死亡案例。
我们呈现了一项多变量分析的结果,该分析控制了死亡原因、死亡时间、死亡地点、妊娠结局、妇女年龄和国籍。
我们检验这样一个假设,即与研究中的其他国家相比,MMR较高的国家因血栓栓塞、高血压、出血或感染导致的直接产科死亡病例比例会更高。我们研究死亡时间和孕产妇年龄,以衡量不同国家组中年龄较大母亲之间是否存在差异。
我们发现在不同MMR水平的国家之间,死亡原因、时间以及年龄特异性死亡率存在明显模式。
尽管欧洲的孕产妇死亡率较低,但国家间在死亡原因、时间以及孕产妇年龄方面存在差异模式。除了作为一个国家健康状况的重要指标外,欧洲国家间MMR的差异还能让我们了解产科护理在孕产妇死亡中所起作用的情况。