Oefelein Michael G
Case Western Reserve University, Department of Urology, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA.
World J Urol. 2004 Oct;22(4):267-71. doi: 10.1007/s00345-003-0388-2. Epub 2004 Jan 16.
The aim of this work was to evaluate variables that predict time to pad-free urinary continence after anatomical radical prostatectomy (ARP). Sixty consecutive prostate cancer patients who underwent ARP by one surgeon were studied. Pad-free urinary continence was prospectively determined by patient interviews and confirmed on physical examination and by the urinary domain of the Extended Prostate Inventory Composite (EPIC) Health Related Quality of Life questionnaire. A time-dependent Cox multivariate regression analysis was performed to determine which variables significantly correlated with time to pad-free urinary continence. Increasing prostate size (cc), increasing prostate urethral length (cm) and surgical technique (wide excision of the neuro-vascular bundle) correlated with a significantly (P<0.05) prolonged time to achieve pad-free urinary continence. In conclusion, prostate size and surgical technique were the most useful variables in predicting time to pad-free urinary continence after ARP.
这项研究的目的是评估在解剖性根治性前列腺切除术(ARP)后预测无尿垫尿失禁时间的变量。对由同一位外科医生实施ARP的60例连续前列腺癌患者进行了研究。通过患者访谈前瞻性地确定无尿垫尿失禁情况,并通过体格检查以及《前列腺综合扩展量表》(EPIC)健康相关生活质量问卷中的排尿领域进行确认。进行了时间依赖性Cox多变量回归分析,以确定哪些变量与无尿垫尿失禁时间显著相关。前列腺体积增加(立方厘米)、前列腺尿道长度增加(厘米)和手术技术(广泛切除神经血管束)与达到无尿垫尿失禁的时间显著延长(P<0.05)相关。总之,前列腺体积和手术技术是预测ARP后无尿垫尿失禁时间最有用的变量。