Participation of the bacterial membrane in DNA replication and chromosome partition.

The concept that the bacterial membrane plays an active role in the regulation of DNA replication and in segregation, or 'partition', of the bacterial chromosome at cell division was proposed in 1963. Membrane participation offered a relatively simple way to coordinate replication and partition. Some of the details of this model have been confirmed, while others have been changed. In fact, it appears that the membrane may play several distinct roles in these processes, and recent experiments have begun to identify the complexity of membrane involvement.