Saatci E, Miller D M, Stell I M, Lee K C, Moxham J
Division of Engineering, King's College London, UK.
Eur Respir J. 2004 Jan;23(1):129-35. doi: 10.1183/09031936.03.00039503.
The aim of this study was to determine what the influence of different designs of face masks and different noninvasive ventilator modes would be upon total dynamic dead space. Using a spontaneous breathing model, total dynamic dead space was measured when using 19 commercially available face masks and a range of ventilators in various ventilation modes. Total dynamic dead space during spontaneous ventilation was increased above physiological dead space from 32% to 42% of tidal volume by using face masks. The use of noninvasive ventilation modes such as bilevel and continuous positive airway pressure, with continuous pressure throughout the expiratory phase, reduced total dynamic dead space to approach physiological dead space with most face masks. Pressure assist and pressure support ventilation decreased total dynamic dead space to a lesser degree, from 42% to 39% of tidal volume. Face masks with expiratory ports over the nasal bridge resulted in beneficial flow characteristics within the face mask and nasal cavity, so as to decrease total dynamic dead space to less than physiological dead space from 42% to 28.5% of tidal volume. Exhaust ports over the nasal bridge in face masks effect important decreases in dynamic dead space provided positive pressure throughout the expiratory phase is used.
本研究的目的是确定不同设计的面罩和不同的无创通气模式对总动态死腔有何影响。使用自主呼吸模型,在使用19种市售面罩和一系列处于各种通气模式的呼吸机时测量总动态死腔。使用面罩时,自主通气期间的总动态死腔比生理死腔增加,占潮气量的32%至42%。使用双水平和持续气道正压等无创通气模式,在整个呼气阶段保持持续压力,使用大多数面罩时可将总动态死腔降低至接近生理死腔。压力辅助通气和压力支持通气将总动态死腔降低的程度较小,从潮气量的42%降至39%。鼻梁上方带有呼气口的面罩在面罩和鼻腔内产生了有益的气流特性,从而将总动态死腔从潮气量的42%降至28.5%,低于生理死腔。如果在整个呼气阶段使用正压,面罩鼻梁上方的排气口可显著降低动态死腔。