来自晚香玉新鲜块茎的螺旋甾烷醇和呋甾烷醇糖苷。

Spirostanol and furostanol glycosides from the fresh tubers of Polianthes tuberosa.

作者信息

Jin Jian-Ming, Zhang Ying-Jun, Yang Chong-Ren

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.

出版信息

J Nat Prod. 2004 Jan;67(1):5-9. doi: 10.1021/np034028a.

DOI:10.1021/np034028a

PMID:14738376

Abstract

Six new steroid glycosides--two spirostanols, polianthosides B and C (1, 2), and four furostanols, polianthosides D-G (3-6)--were isolated from the fresh tubers of Polianthes tuberosa, together with seven known spirostanols (7-13) and a known furostanol (14) saponins. Their structures were elucidated on the basis of spectroscopic analysis and the results of acidic and enzymatic hydrolysis. The cytotoxic activities of 1-14 against HeLa cells are reported.

摘要

从晚香玉的新鲜块茎中分离出六种新的甾体糖苷——两种螺旋甾烷醇，晚香玉苷B和C（1, 2），以及四种呋甾烷醇，晚香玉苷D - G（3 - 6），同时还分离出七种已知的螺旋甾烷醇（7 - 13）和一种已知的呋甾烷醇皂苷（14）。通过光谱分析以及酸水解和酶水解的结果阐明了它们的结构。报道了化合物1 - 14对HeLa细胞的细胞毒性活性。