Tambyraja Andrew L, Murie John A, Chalmers Roderick T A
Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, Scotland.
J Vasc Surg. 2004 Feb;39(2):400-3. doi: 10.1016/j.jvs.2003.07.029.
Ruptured inflammatory abdominal aortic aneurysm (AAA) is relatively rare, and little has been written on the outcome of operative treatment.
Patients undergoing attempted repair of ruptured inflammatory AAA between 1995 and 2001 were included in a retrospective case-cohort study. Demographic, clinical, and operative factors were analyzed, together with in-hospital morbidity, in-hospital mortality, and duration of postoperative hospital stay.
Of 297 patients who underwent attempted operative repair of ruptured AAA, 24 (8%) had an inflammatory aneurysm. Twenty-two patients were men, and two were women; median age was 69 years (range, 51-85 years). Operative findings revealed a contained hematoma in 16 patients (70%), free rupture in 3 patients (13%), aortocaval fistula in 4 patients (17%), and aortoenteric fistula in 1 patient (4%). Of 273 noninflammatory ruptured AAAs, only 2 AAA (1%) were associated with primary aortic fistula. Ten patients (42%) with inflammatory AAA died in hospital, compared with 117 of 273 patients (43%) without inflammation. Median postoperative stay was 10 days (range, 0-35 days). Of the 14 patients with inflammatory lesions who survived, 11 had postoperative complications; 4 patients had acute renal failure, three of whom required temporary renal replacement therapy.
Ruptured inflammatory AAA is associated with a higher incidence of aortic fistula than is ruptured noninflammatory AAA. Repair of ruptured inflammatory AAA is not associated with increased operative mortality compared with repair of ruptured noninflammatory AAA.
炎性腹主动脉瘤破裂相对少见,关于手术治疗的结果鲜有报道。
对1995年至2001年间尝试修复炎性腹主动脉瘤破裂的患者进行回顾性病例队列研究。分析人口统计学、临床和手术因素,以及住院发病率、住院死亡率和术后住院时间。
在297例尝试手术修复腹主动脉瘤破裂的患者中,24例(8%)患有炎性动脉瘤。22例为男性,2例为女性;中位年龄为69岁(范围51 - 85岁)。手术发现16例患者(70%)有局限性血肿,3例患者(13%)为游离破裂,4例患者(17%)为主动脉腔静脉瘘,1例患者(4%)为主动脉肠瘘。在273例非炎性腹主动脉瘤破裂患者中,仅有2例(1%)伴有原发性主动脉瘘。炎性腹主动脉瘤患者中有10例(42%)死于医院,而273例非炎性患者中有117例(43%)死亡。术后中位住院时间为10天(范围0 - 35天)。在14例存活的炎性病变患者中,11例有术后并发症;4例患者发生急性肾衰竭,其中3例需要临时肾脏替代治疗。
与非炎性腹主动脉瘤破裂相比,炎性腹主动脉瘤破裂伴主动脉瘘的发生率更高。与修复非炎性腹主动脉瘤破裂相比,修复炎性腹主动脉瘤破裂的手术死亡率并未增加。