全自动Bactec MGIT 960系统用于结核分枝杆菌对一线药物药敏试验的评估：一项多中心研究。
Evaluation of the fully automated Bactec MGIT 960 system for the susceptibility testing of Mycobacterium tuberculosis to first-line drugs: a multicenter study.
作者信息
Kontos Fanourios, Maniati Maria, Costopoulos Christos, Gitti Zoe, Nicolaou Stavroula, Petinaki Efymia, Anagnostou Spyridoula, Tselentis Ioannis, Maniatis Antonios N
机构信息
Department of Microbiology, Medical School, University Hospital of Larissa, Papakyriazi 22, Larissa, Greece.
出版信息
J Microbiol Methods. 2004 Feb;56(2):291-4. doi: 10.1016/j.mimet.2003.10.015.
The accuracy of the Bactec MGIT 960 system for susceptibility testing of 177 clinical isolates of Mycobacterium tuberculosis to first line drugs (isoniazid, rifampicin, ethambutol and streptomycin) was compared with the agar reference method. The sensitivity, the ability to detect resistance, of the MGIT system was 100%, while the specificity, the ability to detect susceptibility, ranged from 98.6% to 100% for all drugs tested.
将Bactec MGIT 960系统对177株结核分枝杆菌临床分离株进行一线药物（异烟肼、利福平、乙胺丁醇和链霉素）药敏试验的准确性与琼脂参考方法进行了比较。MGIT系统检测耐药性的敏感性为100%，而对于所有测试药物，其检测敏感性的特异性范围为98.6%至100%。
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