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通过充气磁共振结肠成像筛查结肠肿瘤。

Screening of colonic tumors by air-inflated magnetic resonance (MR) colonography.

作者信息

Lam Wynnie W M, Leung Wai K, Wu Justin K L, So Nina M C, Sung Joseph J Y

机构信息

Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong.

出版信息

J Magn Reson Imaging. 2004 Apr;19(4):447-52. doi: 10.1002/jmri.20028.

DOI:10.1002/jmri.20028
PMID:15065168
Abstract

PURPOSE

To assess the accuracy of air-inflated magnetic resonance (MR) colonography for the detection of colonic lesions.

MATERIALS AND METHODS

A total of 36 patients underwent both colonoscopy and air-inflated MR colonography. Breath-hold sequences (volumetric interpolated breath-hold examination (VIBE) coronal, and half-Fourier acquisition single-shot turbo spin-echo (HASTE) axial and coronal, both supine and prone) were performed with a 1.5T scanner. The detection of colonic lesions by MR colonography was then correlated with the findings from the colonoscopy performed on the same day.

RESULTS

Two patients were unable to complete the MR colonography examination. Analysis was based on the results from 34 patients (17 males and 17 females, 38-70 years old, mean age = 54.9 years) who completed both examinations. MR colonography depicted two of two colonic tumors, one of one P4 (> 2 cm) polyp, one of two P2 (0.5-1 cm) polyps, and two of 11 P1 (< 0.5 cm) polyps. False-positive MR colonography interpretations were noted for one P1 polyp and two P2 polyps. The overall sensitivity, positive predictive value, and accuracy of MR colonography were 38%, 67%, and 46.2%, respectively. For the detection of endoluminal lesions > 5 mm, air-inflated MR colonography yielded a sensitivity of 75%, specificity of 93.3%, accuracy of 91.2%, positive predictive value of 60%, and negative predictive value of 96.6%.

CONCLUSION

Air-inflated MR colonography is a new technique that deserves further investigation.

摘要

目的

评估空气充盈磁共振(MR)结肠成像检测结肠病变的准确性。

材料与方法

共有36例患者接受了结肠镜检查和空气充盈MR结肠成像。使用1.5T扫描仪进行屏气序列扫描(容积内插屏气检查(VIBE)冠状位,以及半傅里叶采集单次激发快速自旋回波(HASTE)轴位和冠状位,均包括仰卧位和俯卧位)。然后将MR结肠成像检测到的结肠病变结果与同一天进行的结肠镜检查结果进行对比。

结果

2例患者无法完成MR结肠成像检查。分析基于34例完成两项检查的患者(男性17例,女性17例,年龄38 - 70岁,平均年龄 = 54.9岁)的结果。MR结肠成像显示2例结肠肿瘤中的2例,1例直径大于2 cm的P4息肉中的1例,2例直径0.5 - 1 cm的P2息肉中的1例,以及11例直径小于0.5 cm的P1息肉中的2例。在1例P1息肉和2例P2息肉中发现了MR结肠成像的假阳性解读。MR结肠成像的总体敏感性、阳性预测值和准确性分别为38%、67%和46.2%。对于检测腔内病变大于5 mm,空气充盈MR结肠成像的敏感性为75%,特异性为93.3%,准确性为91.2%,阳性预测值为60%,阴性预测值为96.6%。

结论

空气充盈MR结肠成像是一项值得进一步研究的新技术。

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