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腰椎间盘突出症术后失败综合征:腰椎间盘显微切除术后症状性节段性单节段不稳定的作用。

Failed back surgery syndrome: the role of symptomatic segmental single-level instability after lumbar microdiscectomy.

作者信息

Schaller B

机构信息

Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.

出版信息

Eur Spine J. 2004 May;13(3):193-8. doi: 10.1007/s00586-003-0632-x. Epub 2004 Jan 30.

Abstract

Segmental instability represents one of several different factors that may cause or contribute to the failed back surgery syndrome after lumbar microdiscectomy. As segmental lumbar instability poses diagnostic problems by lack of clear radiological and clinical criteria, only little is known about the occurrence of this phenomenon following primary microdiscectomy. Retrospectively, the records of 2,353 patients were reviewed according to postoperative symptomatic segmental single-level instability after lumbar microdiscectomy between 1989 and 1997. Progressive neurological deficits increased (mean of 24 months; SD: 12, range 1-70) after the initial surgical procedure in 12 patients. The mean age of the four men and eight women was 43 years (SD: 6, range 40-77). The main symptoms and signs of secondary neurological deterioration were radicular pain in 9 of 12 patients, increased motor weakness in 6 of 12 patients and sensory deficits in 4 of 12 patients. All 12 symptomatic patients had radiological evidence of segmental changes correlating with the clinical symptoms and signs. All but one patient showed a decrease in the disc height greater than 30% at the time of posterior spondylodesis compared with the preoperative images before lumbar microdiscectomy. All patients underwent secondary laminectomy and posterior lumbar sponylodesis. Postoperatively, pain improved in 8 of 9 patients, motor weakness in 3 of 6 patients, and sensory deficits in 2 of 4 patients. During the follow-up period of 72+/-7 months, one patient required a third operation to alleviate spinal stenosis at the upper end of the laminectomy. Patients with secondary segmental instability following microdiscectomy were mainly in their 40s. Postoperative narrowing of the intervertebral space following lumbar microdiscectomy is correlated to the degree of intervertebral disc resection. It can therefore be concluded that (1) patients in their 40s are prone to postoperative narrowing of the intervertebral disc space and hence subsequent intervertebral instability and (2) that a small extent of intervertebral disc resection and preservation of the "segmental frame" may be beneficial in those patients. The present study demonstrated for the first time that the degree of extensive operative techniques in microdiscectomy increased the risk of subsequent segmental instability. In addition, narrowing of the intervertebral space of more than 30% represents a clear radiological sign of segmental instability.

摘要

节段性不稳定是腰椎间盘切除术后导致或促成失败的脊柱手术综合征的几种不同因素之一。由于腰椎节段性不稳定缺乏明确的影像学和临床标准,导致诊断困难,因此对于初次腰椎间盘切除术后这种现象的发生了解甚少。回顾性分析1989年至1997年间2353例腰椎间盘切除术后出现症状性节段性单节段不稳定患者的记录。12例患者在初次手术后出现进行性神经功能缺损(平均24个月;标准差:12,范围1 - 70)。4名男性和8名女性的平均年龄为43岁(标准差:6,范围40 - 77)。继发性神经功能恶化的主要症状和体征包括:12例患者中有9例出现神经根性疼痛,12例患者中有6例运动无力加重,12例患者中有4例感觉障碍。所有12例有症状的患者均有与临床症状和体征相关的节段性改变的影像学证据。除1例患者外,所有患者后路脊柱融合术时的椎间盘高度与腰椎间盘切除术前的术前影像相比均下降超过30%。所有患者均接受了二次椎板切除术和后路腰椎融合术。术后,9例患者中有8例疼痛改善,6例患者中有3例运动无力改善,4例患者中有2例感觉障碍改善。在72±7个月的随访期内,1例患者需要进行第三次手术以缓解椎板切除上端的椎管狭窄。腰椎间盘切除术后继发性节段性不稳定的患者主要为40多岁。腰椎间盘切除术后椎间隙变窄与椎间盘切除程度相关。因此可以得出结论:(1)40多岁的患者术后易发生椎间隙变窄,进而导致椎间不稳定;(2)对于这些患者,小范围的椎间盘切除和保留“节段框架”可能有益。本研究首次表明,腰椎间盘切除术中广泛的手术技术程度增加了随后节段性不稳定的风险。此外,椎间隙变窄超过30%是节段性不稳定的明确影像学标志。

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