Borisova T V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(2):217-21.
The author studied 40 patients with hereditary extrapyramidal diseases, including 8 cases with Hallerworden-Spatz disease, 13--with Hutchingtons chorea and 23 with torsion dystonia. For control purposes 20 normals were studied as well. The studies were aimed at determining the iron, manganese and zinc content in the blood plasma in the diurnal urine by means of an atom-absorbtional spectrophotometry on the apparatus "Perkin--Elmer-503" with the use of black lead flasks. These parameters were correlated with the clinical syndrome, severity of the condition and its duration. In order to detect the possible intercorrelations between the trace elements the method of a correlational level with determination of Spearman's coefficient was used.
作者研究了40例遗传性锥体外系疾病患者，其中包括8例哈勒沃登 - 施帕茨病、13例亨廷顿舞蹈病和23例扭转性肌张力障碍。为作对照，还研究了20名正常人。研究旨在通过使用“珀金 - 埃尔默 - 503”仪器、采用石墨炉原子吸收分光光度法测定血浆和日间尿液中的铁、锰和锌含量。将这些参数与临床综合征、病情严重程度及其持续时间进行关联分析。为检测微量元素之间可能存在的相互关系，采用了相关水平法并测定斯皮尔曼系数。
