Markova E D, Solomonov A P, Insarova N G, Larskiĭ E G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(6):830-3.
The authors studied the serotonin content in 43 patients with hereditary extrapyramidal diseases and in 30 normals (the control group). The thrombocyte serotonin was determined according to the modified Crawford method. The results of the study displayed that there was a highly significant drop in the level of serotonin in patients with torsion distonia (more expressed in subgroup 3, in patients with prevalent tonic disturbances and fixed pathological poses), and in akinetico-rigid variants of Huntington's chorea. In patients with hereditary pallidary degenerative diseases there was a tendency to a drop in the serotonin level.
作者研究了43例遗传性锥体外系疾病患者和30名正常人（对照组）的血清素含量。采用改良的克劳福德方法测定血小板血清素。研究结果显示，扭转性肌张力障碍患者（在第3亚组中更明显，即主要为强直性障碍和固定病理姿势的患者）以及亨廷顿舞蹈病的运动不能-强直型变体患者的血清素水平显著下降。遗传性苍白球变性疾病患者的血清素水平有下降趋势。
