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心电图诊断左心室肥厚与高心血管风险相关:来自40至69岁全科队列研究的结果

A diagnosis of left ventricular hypertrophy on ECG is associated with a high cardiovascular risk: findings from a 40- to 69-year-old cohort in general practice.

作者信息

Ciardullo A V, Azzolini L, Bevini M, Cadioli T, Daghio M M, Guidetti P, Lorenzetti M, Malavasi P, Morellini A, Carapezzi C

机构信息

Local Health Plan, Azienda USL, Italy.

出版信息

Fam Pract. 2004 Feb;21(1):63-5. doi: 10.1093/fampra/cmh114.

DOI:10.1093/fampra/cmh114
PMID:14760047
Abstract

OBJECTIVE

Left ventricular hypertrophy (LVH) is an independent cardiovascular (CV) risk factor in both sexes. We studied if a diagnosis of LVH on electrocardiogram (ECG) was associated with a 'high CV risk condition' among 40- to 69-year-old individuals cared for by GPs.

METHODS

We studied 4250 individuals, 5.4% of whom had LVH. Cross-sectional frequencies, and age- and gender-adjusted statistical differences have been calculated.

RESULTS

All the study variables were significantly worse for 'LVH' than 'non-LVH' individuals (except smoking). The 'LVH' had both a mean '5-year CV risk' significantly greater than 'non-LVH' individuals (27.0% versus 8.6%), and a significantly higher prevalence of a '5-year CV risk >15%' (89% versus 15%).

CONCLUSIONS

A diagnosis of LVH on ECG among the adult individuals of an opportunistic cohort from general practice was associated with a 6-fold greater prevalence of a 'high CV risk condition'.

摘要

目的

左心室肥厚(LVH)是男女共有的独立心血管(CV)危险因素。我们研究了在全科医生诊治的40至69岁个体中,心电图(ECG)诊断出的LVH是否与“高心血管风险状况”相关。

方法

我们研究了4250名个体,其中5.4%患有LVH。计算了横断面频率以及年龄和性别调整后的统计学差异。

结果

除吸烟外,所有研究变量在“LVH”个体中均显著差于“非LVH”个体。“LVH”个体的平均“5年心血管风险”显著高于“非LVH”个体(27.0%对8.6%),且“5年心血管风险>15%”的患病率显著更高(89%对15%)。

结论

在全科医疗机会性队列的成年个体中,心电图诊断出LVH与“高心血管风险状况”的患病率高6倍相关。

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