都柏林社区鼻腔携带金黄色葡萄球菌的患病率、抗生素敏感性及噬菌体类型

The prevalence, antibiotic susceptibility and phage-type of nasally carried Staphylococcus aureus in the Dublin community.

作者信息

Shuhaibar M N, Falkiner F R

机构信息

Department of Clinical Microbiology, Trinity College, Dublin.

出版信息

Ir J Med Sci. 1992 Oct;161(10):589-92. doi: 10.1007/BF02942364.

DOI:10.1007/BF02942364

PMID:1478839

Abstract

A study was undertaken to determine the distribution, antibiotic susceptibility and phage type pattern of nasally-carried Staphylococcus aureus in the community. Coagulase-positive staphylococci were isolated from 180 of 440 individuals. The rate was higher in the inner city and among young adults and middle-aged males. The isolates were examined for phage-type patterns and antibiotic susceptibility. Most (60.6%) of the isolates were typable either at Routine Test Dilution (RTD) or at 100 RTD. Most belonged to phage group I (53.2%) and phage group III (21.1%). Susceptibility to penicillin and ampicillin was low at 12.3 and 15.5% respectively. All were susceptible to vancomycin. Methicillin-resistance was unexpectedly low at 0.6% whereas tetracycline and erythromycin resistance were in line with recent trends at 4.5 and 2.7%. The rate of multiple resistance was low at 2.3%.

摘要

开展了一项研究以确定社区中鼻腔携带金黄色葡萄球菌的分布、抗生素敏感性和噬菌体型模式。在440名个体中，从180人分离出凝固酶阳性葡萄球菌。该比率在市中心以及年轻人和中年男性中较高。对分离株进行了噬菌体型模式和抗生素敏感性检测。大多数（60.6%）分离株在常规试验稀释度（RTD）或100 RTD时可分型。大多数属于噬菌体I组（53.2%）和噬菌体III组（21.1%）。对青霉素和氨苄西林的敏感性较低，分别为12.3%和15.5%。所有分离株对万古霉素敏感。耐甲氧西林率出乎意料地低，为0.6%，而四环素和红霉素耐药率与近期趋势一致，分别为4.5%和2.7%。多重耐药率较低，为2.3%。