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位于酵母第十一染色体左臂上一个9.3 kb片段的序列揭示了五个开放阅读框,包括CCE1基因以及与MYO2和核糖体蛋白L10相关的推定产物。

The sequence of a 9.3 kb segment located on the left arm of the yeast chromosome XI reveals five open reading frames including the CCE1 gene and putative products related to MYO2 and to the ribosomal protein L10.

作者信息

Pascolo S, Ghazvini M, Boyer J, Colleaux L, Thierry A, Dujon B

机构信息

Unité de Génétique Moléculaire des Levures (URA 1149 du C.N.R.S.), Institut Pasteur, Paris, France.

出版信息

Yeast. 1992 Nov;8(11):987-95. doi: 10.1002/yea.320081109.

DOI:10.1002/yea.320081109
PMID:1481574
Abstract

We report here the sequence of a 9.3 kb DNA segment of chromosome XI of Saccharomyces cerevisiae, located between the MAK11 locus and the centromere. This sequence contains four long open reading frames (ORFs), YKL160, YKL162, YKL164, YKL165 and part of another ORF, YKL166, covering altogether 90% of the entire sequence. One of these ORFs, YKL164, corresponds to CCE1. Translation products of two other ORFs, YKL160 and YKL165, exhibit homology with previously known S. cerevisiae proteins: the ribosomal protein L10, and the MYO2 gene product, respectively.

摘要

我们在此报告酿酒酵母第十一条染色体上一段9.3 kb DNA片段的序列,该片段位于MAK11基因座和着丝粒之间。此序列包含四个长开放阅读框(ORF),即YKL160、YKL162、YKL164、YKL165以及另一个ORF(YKL166)的一部分,总共覆盖了整个序列的90%。其中一个ORF,YKL164,对应于CCE1。另外两个ORF,YKL160和YKL165的翻译产物分别与先前已知的酿酒酵母蛋白:核糖体蛋白L10和MYO2基因产物具有同源性。

相似文献

1
The sequence of a 9.3 kb segment located on the left arm of the yeast chromosome XI reveals five open reading frames including the CCE1 gene and putative products related to MYO2 and to the ribosomal protein L10.位于酵母第十一染色体左臂上一个9.3 kb片段的序列揭示了五个开放阅读框,包括CCE1基因以及与MYO2和核糖体蛋白L10相关的推定产物。
Yeast. 1992 Nov;8(11):987-95. doi: 10.1002/yea.320081109.
2
The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene.来自酿酒酵母二号染色体右臂上一个33 kb片段的完整序列揭示了16个开放阅读框,其中包括10个新的开放阅读框、5个先前已鉴定的基因以及SCO1基因的一个同源物。
Yeast. 1994 Apr;10 Suppl A:S75-80. doi: 10.1002/yea.320100010.
3
Sequencing and analysis of a 20.5 kb DNA segment located on the left arm of yeast chromosome XI.对位于酵母第十一染色体左臂上的一段20.5千碱基对DNA片段进行测序和分析。
Yeast. 1994 Apr;10 Suppl A:S25-33. doi: 10.1002/yea.320100004.
4
The sequence of a nearly unclonable 22.8 kb segment on the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames.来自酿酒酵母七号染色体左臂上一段近22.8 kb、几乎无法克隆的片段的序列揭示了ARO2、RPL9A、TIP1、MRF1基因以及六个新的开放阅读框。
Yeast. 1997 Feb;13(2):177-82. doi: 10.1002/(SICI)1097-0061(199702)13:2<177::AID-YEA62>3.0.CO;2-2.
5
The sequence of a 32,420 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae.位于酿酒酵母二号染色体右臂上的一段32420碱基对片段的序列。
Yeast. 1994 Apr;10 Suppl A:S47-62. doi: 10.1002/yea.320100007.
6
Sequence of a 12.7 kb segment of yeast chromosome II identifies a PDR-like gene and several new open reading frames.酵母二号染色体12.7 kb片段的序列鉴定出一个类PDR基因和几个新的开放阅读框。
Yeast. 1992 Sep;8(9):761-8. doi: 10.1002/yea.320080909.
7
DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae.对酿酒酵母11号染色体上位于FAS1和LAP基因座之间的一个36.2 kb片段进行DNA测序。
Yeast. 1994 Apr;10 Suppl A:S35-40. doi: 10.1002/yea.320100005.
8
A 12.8 kb segment, on the right arm of chromosome II from Saccharomyces cerevisiae including part of the DUR1,2 gene, contains five putative new genes.来自酿酒酵母二号染色体右臂的一个12.8千碱基片段,包括部分DUR1,2基因,含有五个推定的新基因。
Yeast. 1993 Jul;9(7):797-806. doi: 10.1002/yea.320090714.
9
Sequence analysis of a 3.5 Kb EcoRI fragment from the left arm of Saccharomyces cerevisiae chromosome XI reveals the location of the MBR1 gene and a sequence related to a GTPase-activating protein.对酿酒酵母第十一染色体左臂上一个3.5千碱基对的EcoRI片段进行序列分析,揭示了MBR1基因的位置以及一个与GTP酶激活蛋白相关的序列。
Yeast. 1994 Feb;10(2):257-64. doi: 10.1002/yea.320100212.
10
The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes.酵母X染色体左臂上一段36 kb片段的序列鉴定出24个开放阅读框,包括NUC1、PRP21(SPP91)、CDC6、CRY2、S24基因、乌头酸酶基因ACO1的一个同源物以及与III号染色体基因的两个同源物。
Yeast. 1994 Sep;10(9):1235-49. doi: 10.1002/yea.320100912.

引用本文的文献

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Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle.鉴定Prp40,一种与U1小核核糖核蛋白颗粒相关的新型必需酵母剪接因子。
Mol Cell Biol. 1996 Mar;16(3):960-7. doi: 10.1128/MCB.16.3.960.
2
Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.formin结合蛋白带有WWP/WW结构域,该结构域可结合富含脯氨酸的肽段,其功能类似于SH3结构域。
EMBO J. 1996 Mar 1;15(5):1045-54.
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EMBO J. 1995 May 15;14(10):2326-32. doi: 10.1002/j.1460-2075.1995.tb07227.x.