McMillan T A, Stewart W C, Hennis H L, Hunt H H, Apple D J
Department of Ophthalmology, Medical University of South Carolina, Charleston 29425-2236.
Ophthalmic Surg. 1992 Nov;23(11):762-5.
We compared perioperative conjunctival biopsy specimens from 31 consecutive trabeculectomy patients to determine if there were any histologic differences between black and white glaucoma patients. We found a statistically significantly greater mean and distribution of mast cells and neutrophils in the white patients. No significant difference was found in the mean number of goblet cells, eosinophiles, macrophages, fibroblasts, plasma cells, or lymphocytes; or in thickness of the epithelium, vascular density, or collagen or mucopolysaccharide staining. We conclude that histological conjunctival factors that could be evaluated preoperatively probably are not related to the poor results in black patients of filtration surgery noted by some investigators.
我们比较了31例连续小梁切除术患者的围手术期结膜活检标本，以确定黑人和白人青光眼患者之间是否存在任何组织学差异。我们发现白人患者中肥大细胞和中性粒细胞的平均数量及分布在统计学上显著更高。杯状细胞、嗜酸性粒细胞、巨噬细胞、成纤维细胞、浆细胞或淋巴细胞的平均数量；或上皮厚度、血管密度、胶原或粘多糖染色方面均未发现显著差异。我们得出结论，术前可评估的结膜组织学因素可能与一些研究者指出的黑人患者滤过手术效果不佳无关。
