Spriggs D A, French J M, Murdy J M, Curless R H, Bates D, James O F
Department of Medicine (Geriatrics), University of Newcastle upon Tyne.
Q J Med. 1992 Jul;83(303):555-62.
In a case-controlled study we recruited 400 patients admitted to hospital with stroke and 400 community controls matched for age, gender and family practitioner. Snoring history was obtained from 326 patients and 345 controls. Odds ratio for admission to hospital with stroke was 3.2 (95 per cent confidence intervals 2.3-4.4) for regular snorers against those who did not snore regularly. This risk was independent for age, gender and other risk factors for stroke. Snoring did not increase the chances of stroke during sleep. Level of consciousness was reduced more frequently in snorers (p = 0.0003). As the frequency of snoring increased so did the mortality to 6 months (p = 0.0006). Snoring is an important risk factor for stroke and adversely affects the prognosis in patients admitted to hospital with stroke.
在一项病例对照研究中，我们招募了400名因中风入院的患者以及400名在年龄、性别和家庭医生方面相匹配的社区对照者。从326名患者和345名对照者那里获取了打鼾病史。经常打鼾者与不经常打鼾者相比，因中风入院的比值比为3.2（95%置信区间为2.3 - 4.4）。这种风险独立于年龄、性别和其他中风风险因素。打鼾并未增加睡眠期间中风的几率。打鼾者意识水平降低更为频繁（p = 0.0003）。随着打鼾频率增加，至6个月时的死亡率也增加（p = 0.0006）。打鼾是中风的一个重要风险因素，并且对因中风入院的患者的预后有不利影响。
